Overall Survival Results with Surgical Treatment After Neoadjuvant Chemotherapy in Local Invasive Gastric Cancers

Abstract

Objectives: Gastric cancer is a very common and fatal cancer. The only known curative treatment is radical gastrectomy. This retrospective study compared the overall survival results of surgical treatment after neoadjuvant chemotherapy and standard surgical treatment. Methods: The records of 90 patients from a single center who had locally invasive gastric cancer were evaluated retrospectively. Of those, 45 patients (50%) underwent neoadjuvant chemotherapy and surgical treatment. Results: Patients who underwent surgical treatment after neoadjuvant chemotherapy for locally invasive gastric cancer were found to have a general survival time of 16.6 months, while it was 15.6 months for those who pursued standard surgical treatment. Conclusion: In this study, there was no significant difference in terms of overall survival between surgical treatment after neoadjuvant chemotherapy and standard surgical treatment for patients with gastric cancer.