Surface functionalization of phosphate-based bioactive glasses with 3-aminopropyltriethoxysilane (APTS)

Q1 Materials Science

Biomedical Glasses Pub Date : 2016-01-05 DOI:10.1515/bglass-2016-0007

J. Massera, A. Mishra, S. Guastella, S. Ferraris, E. Verné

引用次数: 9

Abstract

Abstract The effect of SrO substitution for CaO, in the 50P2O5-10Na2O-(40-x)CaO-xSrO glass system, on the ability to graft 3-aminopropyltriethoxysilane (APTS) at the glass surface has been investigated and is partially compared to changes occurring further from the surface. The step used for the APTS grafting led to Na leaching and successively to Ca and/or Sr leaching. This gave rise to a P2O5- rich glass surface, especially on sample containing both Ca and Sr ions. The hydration of the phosphate chainswas found to be the most pronounced for the glasses containing large quantity of SrO as evidenced by contact angle and X-ray photoelectron spectroscopy (XPS). The increase in phosphate chain hydration was attributed to the expansion of the glass network when Sr ions are introduced. Finally, based on the N1s XPS peak, N species were found at the surface of the glasses in two configurations: NH2 and – NH2-OH as proof of APTS grafting. APTS grafting on phosphate glass is of importance for the grafting of proteins.

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3-氨基丙基三乙氧基硅烷(APTS)表面功能化磷酸酯基生物活性玻璃

摘要研究了50P2O5-10Na2O-(40-x)CaO- xsro玻璃体系中SrO取代CaO对玻璃表面接枝3-氨基丙基三乙氧基硅烷(APTS)能力的影响，并将其与表面以外发生的变化进行了部分比较。APTS接枝的步骤导致Na浸出，然后是Ca和/或Sr浸出。这就产生了富含P2O5的玻璃表面，特别是在同时含有Ca和Sr离子的样品上。接触角和x射线光电子能谱(XPS)证明，磷酸盐链的水化作用在含有大量SrO的玻璃中最为明显。磷酸链水化的增加是由于锶离子的引入使玻璃网膨胀。最后，根据N1s的XPS峰，在玻璃表面发现了NH2和- NH2- oh两种构型的N种，证明了APTS接枝的存在。磷酸玻璃上的APTS接枝对于蛋白质的接枝具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biomedical Glasses Materials Science-Surfaces, Coatings and Films

自引率

0.00%

发文量

审稿时长

17 weeks

期刊介绍： Biomedical Glasses is an international Open Access-only journal covering the field of glasses for biomedical applications. The scope of the journal covers the science and technology of glasses and glass-based materials intended for applications in medicine and dentistry. It includes: Chemistry, physics, structure, design and characterization of biomedical glasses Surface science and interactions of biomedical glasses with aqueous and biological media Modeling structure and reactivity of biomedical glasses and their interfaces Biocompatibility of biomedical glasses Processing of biomedical glasses to achieve specific forms and functionality Biomedical glass coatings and composites In vitro and in vivo evaluation of biomedical glasses Glasses and glass-ceramics in engineered regeneration of tissues and organs Glass-based devices for medical and dental applications Application of glasses and glass-ceramics in healthcare.