Seasonal Variations of Hospital Admissions for Alcohol-Related Hepatitis in the United States.

IF 1.4 Q4 GASTROENTEROLOGY & HEPATOLOGY
Gastroenterology Research Pub Date : 2022-04-01 Epub Date: 2022-04-23 DOI:10.14740/gr1506
Aalam Sohal, Kanwal Bains, Armaan Dhaliwal, Hunza Chaudhry, Raghav Sharma, Piyush Singla, Gagan Gupta, Dino Dukovic, Sunny Sandhu, Marina Roytman, Steven Tringali
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Abstract

Background: Clinical experience suggests an increased hospitalization rate for alcohol-related hepatitis (AH) in the winter months; however, seasonal variations in the prevalence of hospitalizations for AH have not been described previously. We hypothesized that AH hospitalizations would be higher in the winter months due to the holiday season and increased alcohol sales.

Methods: Patients with primary or secondary discharge diagnosis of AH were included in the study (International Classification of Diseases, Clinical Modification-10th Revision codes K70.4 and K70.1) between January 2016 and December 2019. The primary outcome measure for this study was daily hospitalizations by each month of the year. Secondary outcome measures included the rate of in-hospital mortality associated with AH, for each month.

Results: The highest number of AH-related admissions was reported in July (n = 56,800; 9%), followed by August (n = 55,700; 8.8%) and May (n = 54,865; 8.7%). February had the lowest number of admissions (n = 46,550; 7.37%). The adjusted mortality was highest in December (overall mortality: 9.6%; adjusted odds ratio: 1.29; 95% confidence interval: 1.142 - 1.461; P < 0.0001) and lowest in May (overall mortality rate: 7.7%). No difference was noted between length of stay and total hospitalization cost between months.

Conclusion: Our findings demonstrate that seasonal variations in hospitalizations related to AH do exist across the United States. Regional differences also exist and follow unique patterns. The increase in admissions for AH is in line with other studies suggesting that heavy drinking happens during the warm season. Hospital administrators and other stewards of healthcare resources can use seasonal patterns to guide allocation of resources.

美国酒精相关肝炎入院人数的季节性变化。
背景:临床经验表明,酒精相关肝炎(AH)的住院率在冬季会有所上升;然而,此前并未描述过酒精相关肝炎住院率的季节性变化。我们假设,由于节假日和酒精销售量的增加,冬季的酒精相关性肝炎住院率会更高:研究纳入了 2016 年 1 月至 2019 年 12 月期间主要或次要出院诊断为 AH 的患者(《国际疾病分类、临床修订-10 次修订》代码 K70.4 和 K70.1)。本研究的主要结果测量指标是每年每月的日住院率。次要结果指标包括每月与 AH 相关的院内死亡率:与 AH 相关的住院人数最多的月份是 7 月(n = 56,800; 9%),其次是 8 月(n = 55,700; 8.8%)和 5 月(n = 54,865; 8.7%)。二月份的入院人数最少(人数=46,550;7.37%)。调整后的死亡率在 12 月份最高(总死亡率:9.6%;调整后的几率比:1.29;95% 置信区间:1.142 - 1.461;P < 0.0001),在 5 月份最低(总死亡率:7.7%)。不同月份的住院时间和住院总费用没有差异:我们的研究结果表明,在美国各地,与 AH 相关的住院治疗确实存在季节性差异。地区之间也存在差异,并遵循独特的模式。AH入院人数的增加与其他研究结果一致,表明在温暖的季节会出现大量饮酒的情况。医院管理者和其他医疗资源的管理者可以利用季节性模式来指导资源分配。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Gastroenterology Research
Gastroenterology Research GASTROENTEROLOGY & HEPATOLOGY-
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