Recent advances in chemical synthesis of O-linked glycopeptides and glycoproteins: An advanced synthetic tool for exploring the biological realm

IF 5.3 2区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Nano Materials Pub Date : 2023-10-26 DOI:10.1016/j.cbpa.2023.102405

Jie Zhao , Farong Ye , Ping Huang , Ping Wang

引用次数: 0

Abstract

Glycoproteins play crucial roles in various biological processes. To investigate the relationship between glycan structure and function, researchers have employed various chemical methods to precisely synthesize homogeneous O-glycoproteins. This review summarizes the recent progress of their synthetic strategies, highlighting the significant advancements in this area.

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O-连接糖肽和糖蛋白化学合成的最新进展：探索生物学领域的先进合成工具。

糖蛋白在各种生物过程中起着至关重要的作用。为了研究聚糖结构和功能之间的关系，研究人员采用了各种化学方法来精确合成同质O-糖蛋白。这篇综述总结了他们综合战略的最新进展，强调了这一领域的重大进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Nano Materials Multiple-

CiteScore

8.30

自引率

3.40%

发文量

1601

期刊介绍： ACS Applied Nano Materials is an interdisciplinary journal publishing original research covering all aspects of engineering, chemistry, physics and biology relevant to applications of nanomaterials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important applications of nanomaterials.