Eleonora M. Hogan, A. Lipnik, Sarah Anstead, R. Kennedy
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引用次数: 0
Abstract
A program has been written to transfer a set of discontinuous samples in 96-well storage plates to archival plates using an 80-well format. One thousand samples per day can be processed in this manner. The software can handle different sample volumes, random sample locations, and varying concentrations. This program was implemented on a Beckman (Fullerton, CA) Biomek(r) 2000 Laboratory Automation Workstation* using Beckman's BioScript software, BioWorks 1.4A, Tool Command language, and Microsoft (Redmond, WA) Visual Basic™. This system provides an effective means of selecting and transferring discrete samples.
期刊介绍:
Advancing the Science of Drug Discovery: SLAS Discovery reports how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease.
SLAS Discovery is a peer-reviewed journal that publishes scientific reports that enable and improve target validation, evaluate current drug discovery technologies, provide novel research tools, and incorporate research approaches that enhance depth of knowledge and drug discovery success.
SLAS Discovery emphasizes scientific and technical advances in target identification/validation (including chemical probes, RNA silencing, gene editing technologies); biomarker discovery; assay development; virtual, medium- or high-throughput screening (biochemical and biological, biophysical, phenotypic, toxicological, ADME); lead generation/optimization; chemical biology; and informatics (data analysis, image analysis, statistics, bio- and chemo-informatics). Review articles on target biology, new paradigms in drug discovery and advances in drug discovery technologies.
SLAS Discovery is of particular interest to those involved in analytical chemistry, applied microbiology, automation, biochemistry, bioengineering, biomedical optics, biotechnology, bioinformatics, cell biology, DNA science and technology, genetics, information technology, medicinal chemistry, molecular biology, natural products chemistry, organic chemistry, pharmacology, spectroscopy, and toxicology.