Using DNA markers to predict genetic susceptibility to atherosclerosis

Abstract

By seeking DNA markers, or restriction fragment length polymorphisms (RFLPs), associated with the presence of atherosclerosis in clinically relevant populations, investigators in the field of molecular genetics make use of the role played by various genetic components in the genesis of the disease to develop prognostic tests which identify those individuals who carry an underlying genetic predisposition to develop atherosclerotic cardiovascular disease