{"title":"Animal Models: The Watanabe Heritable Hyperlipidemic Rabbit","authors":"B. J. Lenten","doi":"10.1159/000416892","DOIUrl":null,"url":null,"abstract":"An exciting animal model has become available that closely resembles human FH. Named after the investigator who first developed the strain, the Watanabe Heritable Hyperlipidemic (WHHL) rabbit has markedly elevated plasma cholesterol levels and spontaneously develops atherosclerosis and tissue xanthoma","PeriodicalId":76182,"journal":{"name":"Monographs in human genetics","volume":"12 1","pages":"125-138"},"PeriodicalIF":0.0000,"publicationDate":"1989-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000416892","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monographs in human genetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000416892","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
An exciting animal model has become available that closely resembles human FH. Named after the investigator who first developed the strain, the Watanabe Heritable Hyperlipidemic (WHHL) rabbit has markedly elevated plasma cholesterol levels and spontaneously develops atherosclerosis and tissue xanthoma