Younghye Kim, Youngran Kang, Eui Seok Lee, Aeree Kim
{"title":"Angiomyolipoma of the lower lip: A case report and review of the published work","authors":"Younghye Kim, Youngran Kang, Eui Seok Lee, Aeree Kim","doi":"10.1111/j.1755-9294.2011.01096.x","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Angiomyolipoma (AML) in the oral cavity is extremely rare. Their histological features are characterized by admixtures of blood vessels, smooth muscles and mature adipose tissues. We report a case of sporadic AML in the lower lip of a 56-year-old man. Clinically, it presented as a mucocele-like lesion. An excised specimen showed a well-circumscribed, 1.3 cm × 1.0 cm × 0.8 cm-sized, yellowish mass, composed of blood vessels, smooth muscles and mature adipose tissues. These were not epithelioid cells and immunohistochemical stain for human melanoma black (HMB)-45 was negative. Extrarenal AML usually is not associated with tuberous sclerosis and has no HMB-45 immunoreactive cells although it shares the terminology with renal AML. It is regarded as benign. Surgical excision is considered curative.</p>\n </div>","PeriodicalId":92990,"journal":{"name":"Basic and applied pathology","volume":"4 1","pages":"18-20"},"PeriodicalIF":0.0000,"publicationDate":"2011-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1755-9294.2011.01096.x","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Basic and applied pathology","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/j.1755-9294.2011.01096.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Angiomyolipoma (AML) in the oral cavity is extremely rare. Their histological features are characterized by admixtures of blood vessels, smooth muscles and mature adipose tissues. We report a case of sporadic AML in the lower lip of a 56-year-old man. Clinically, it presented as a mucocele-like lesion. An excised specimen showed a well-circumscribed, 1.3 cm × 1.0 cm × 0.8 cm-sized, yellowish mass, composed of blood vessels, smooth muscles and mature adipose tissues. These were not epithelioid cells and immunohistochemical stain for human melanoma black (HMB)-45 was negative. Extrarenal AML usually is not associated with tuberous sclerosis and has no HMB-45 immunoreactive cells although it shares the terminology with renal AML. It is regarded as benign. Surgical excision is considered curative.
摘要口腔血管平滑肌脂肪瘤(AML)极为罕见。它们的组织学特征是血管、平滑肌和成熟脂肪组织的混合物。我们报告一个56岁男性下唇散发性AML病例。临床表现为粘液样病变。切除标本显示一个边界清晰，1.3 cm × 1.0 cm × 0.8 cm大小的淡黄色肿块，由血管、平滑肌和成熟脂肪组织组成。这些细胞不是上皮样细胞，人类黑黑色素瘤免疫组化染色(HMB)-45为阴性。肾外AML通常与结节性硬化无关，也没有HMB-45免疫反应细胞，尽管它与肾性AML有相同的术语。它被认为是良性的。手术切除被认为是可治愈的。
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