Reviews and Resources:Metabolism and Bacterial Pathogenesis: BOOKS

Abstract

“Although several factors could theoretically contribute to a microorganism's ability to colonize the intestinal ecosystem, effective completion for nutrients is paramount to success.” So the editors reference researcher Rolf Freter in their introduction to this new, integrative text. This volume highlights this truth with a biochemical focus on bacterial pathogens and the human host. This includes chapters on enteric, respiratory, urinary tract, and intracellular pathogens. Some chapters also focus attention on the role of commensal communities, such as in dental plaque or in the gut through interaction with host immunity. More species-specific topics include central carbon metabolism by Borrelia burgdorferi, regulation of Escherichia coli fimbriae by host sialic acid, and Pseudomonas aeruginosa metabolism during infection of cystic fibrosis patients. Though it is sparse in its figures, this is a timely and information-rich collection that should be a welcome resource for many microbiologists.