Do you get what you see? The illicit doping market in Denmark—An analysis of performance and image enhancing drugs seized by the police over a 1-year period

IF 2.6 3区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Pia Johansson Heinsvig, Ask Vest Christiansen, Daniel Ayoubi, Laura Smedegaard Heisel, Christian Lindholst
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Abstract

This study examines doping products seized by the police in three regional police districts in Denmark from December 2019 to December 2020. The products, often referred to as performance and image-enhancing drugs (PIEDs), are described in relation to the country of origin, manufacturing company, and the active pharmaceutical ingredient (API) stated on the packaging versus the one identified by subsequent chemical analysis. The study also includes a description of the degree of professionalism by which the products appear according to EU requirements. A total of 764 products were seized during the study period. The products originate from 37 countries, mainly located in Asia (37%), Europe (23%), and North America (13%). One hundred ninety-three different manufacturing companies could be identified from the product packaging. The most frequent compound class was the androgenic anabolic steroids, found in 60% of the products. In 25%–34% of the products, either no or an incorrect API relative to the one stated on the product was found. However, only 7%–10% contain either no API or a compound from a different compound class than the one stated. Most products had a professional appearance fulfilling most EU requirements for packaging information. The study shows that many different companies supply PIEDs to the Danish market and that counterfeit and substandard products are widespread. Many products do, however, appear professional to the user giving an impression of a high-quality product. Although many products are substandard, they most often contain an API from the same compound class as the one labeled.

Abstract Image

你看到什么了吗?丹麦的非法兴奋剂市场——对一年来警方缴获的提高成绩和形象的药物的分析
这项研究调查了2019年12月至2020年12月丹麦三个地区警区警方缴获的兴奋剂产品。这些产品通常被称为性能和图像增强药物(PIED),根据原产国、生产公司和包装上注明的活性药物成分(API)与随后的化学分析确定的活性药物进行描述。该研究还包括对产品按照欧盟要求出现的专业程度的描述。在研究期间,共缉获764种产品。产品来自37个国家,主要分布在亚洲(37%)、欧洲(23%)和北美(13%)。从产品包装中可以识别出193家不同的制造公司。最常见的化合物类别是雄激素合成代谢类固醇,在60%的产品中发现。在25%至34%的产品中,没有发现或发现与产品上所述API相关的不正确的API。然而,只有7%至10%不含API或含有与所述化合物类别不同的化合物。大多数产品都具有专业的外观,符合欧盟对包装信息的大多数要求。研究表明,许多不同的公司向丹麦市场供应PIED,假冒和不合格产品普遍存在。然而,许多产品在用户看来确实很专业,给人一种高质量产品的印象。尽管许多产品不合格,但它们通常含有与标签相同的化合物类别的API。
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来源期刊
Drug Testing and Analysis
Drug Testing and Analysis BIOCHEMICAL RESEARCH METHODS-CHEMISTRY, ANALYTICAL
CiteScore
5.90
自引率
24.10%
发文量
191
审稿时长
2.3 months
期刊介绍: As the incidence of drugs escalates in 21st century living, their detection and analysis have become increasingly important. Sport, the workplace, crime investigation, homeland security, the pharmaceutical industry and the environment are just some of the high profile arenas in which analytical testing has provided an important investigative tool for uncovering the presence of extraneous substances. In addition to the usual publishing fare of primary research articles, case reports and letters, Drug Testing and Analysis offers a unique combination of; ‘How to’ material such as ‘Tutorials’ and ‘Reviews’, Speculative pieces (‘Commentaries’ and ‘Perspectives'', providing a broader scientific and social context to the aspects of analytical testing), ‘Annual banned substance reviews’ (delivering a critical evaluation of the methods used in the characterization of established and newly outlawed compounds). Rather than focus on the application of a single technique, Drug Testing and Analysis employs a unique multidisciplinary approach to the field of controversial compound determination. Papers discussing chromatography, mass spectrometry, immunological approaches, 1D/2D gel electrophoresis, to name just a few select methods, are welcomed where their application is related to any of the six key topics listed below.
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