Susanne Aschhoff , Karl-Christian Schroff , Dieter B. Wildenauer , Elmar Richter
{"title":"Nicotine consumption of several mouse strains using a two bottle choice paradigm","authors":"Susanne Aschhoff , Karl-Christian Schroff , Dieter B. Wildenauer , Elmar Richter","doi":"10.1016/S0939-8600(00)80009-7","DOIUrl":null,"url":null,"abstract":"<div><p>The two bottle choice paradigm provides a convenient method for the rapid screening of preferences of nicotine and a variety of other substances in rodents. A non-expensive, home-made bottle system with low fluid loss due to leakage or evaporation is introduced. Using this system, we tested nicotine preference of the mouse strains NMRI, C3H/J, DBA/2, ST/bJ, C57BL/6 and a cross between male A/J and female NMRI. Our results show different nicotine preference of tested mice with high nicotine preference of C57BL/6, a lower preference of C3H/J, A/J×NMRI, DBA/2 and NMRI and the lowest of ST/bJ.</p></div>","PeriodicalId":77206,"journal":{"name":"Journal of experimental animal science","volume":"40 4","pages":"Pages 171-177"},"PeriodicalIF":0.0000,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0939-8600(00)80009-7","citationCount":"26","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of experimental animal science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0939860000800097","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 26
Abstract
The two bottle choice paradigm provides a convenient method for the rapid screening of preferences of nicotine and a variety of other substances in rodents. A non-expensive, home-made bottle system with low fluid loss due to leakage or evaporation is introduced. Using this system, we tested nicotine preference of the mouse strains NMRI, C3H/J, DBA/2, ST/bJ, C57BL/6 and a cross between male A/J and female NMRI. Our results show different nicotine preference of tested mice with high nicotine preference of C57BL/6, a lower preference of C3H/J, A/J×NMRI, DBA/2 and NMRI and the lowest of ST/bJ.