Antioxidant Effects of Oats Avenanthramides on Human Serum

Agricultural Sciences in China Pub Date : 2011-08-01 DOI:10.1016/S1671-2927(11)60122-3

Sen LIU , Nan YANG , Zhao-hua HOU , Yang YAO , Li LÜ , Xian-rong ZHOU , Gui-xing REN

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引用次数: 30

Abstract

The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study. Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon. Plasma lipid peroxides and antioxidant status were measured. For 8 capsules (containing 3.12 mg avenanthramides) groups, the levels of serum Superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantly increased by 8.4 and 17.9%, respectively (P<0.05), and malondialdehyde (MDA) level significantly decreased by 28.1%. The total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1, 28.1, and 15.1%, respectively (P<0.05). The high density blood lipoprotein cholesterol (HDL-C) levels in the same treat was increased by 13.2%. Based on our research, it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans. It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy.

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燕麦avenanthrides对人血清的抗氧化作用

本研究评价了燕麦avenanthrides胶囊对人体的抗氧化能力。健康的人被随机分配到燕麦来源的燕麦胺胶囊或安慰剂组，持续1个月。测量血浆脂质过氧化物和抗氧化状态。8个胶囊组(含3.12 mg avenanthramides)血清超氧化物歧化酶(SOD)和还原性谷胱甘肽激素(GSH)水平分别显著升高了8.4%和17.9% (P<0.05)，丙二醛(MDA)水平显著降低了28.1%。总胆固醇(TC)、甘油三酯(TG)和低密度脂蛋白胆固醇(LDL-C)水平分别降低11.1、28.1%和15.1% (P<0.05)。高密度脂蛋白胆固醇(HDL-C)水平在同样的治疗中增加了13.2%。根据我们的研究，燕麦提取物含有燕麦烷胺类物质，对人体具有较高的抗氧化活性。提示燕麦avenanthrides可用于预防高脂血症和心血管病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Agricultural Sciences in China AGRICULTURE, MULTIDISCIPLINARY-

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审稿时长

3.2 months