Mejorar la prevención de la trombosis y las complicaciones cardiovasculares durante la pandemia de COVID-19

Abstract

Cardiovascular complications are common in patients with coronavirus disease 2019 (COVID-19), particularly in severe cases: up to 10-30% of hospitalized COVID-19 patients are affected and there is an associated increase in mortality. Important cardiovascular complications include: acute coronary syndrome; acute myocardial injury (elevated troponin levels with normal coronary arteries); arrhythmias (mainly atrial fibrillation and ventricular arrhythmias); heart failure; pericarditis or pericardial effusion; and thromboembolic events (e.g. arterial and venous thromboembolism, microvascular thrombosis, pulmonary embolism, and stroke). Therefore, one of the aims of treatment for patients with COVID-19, particularly in its most serious forms, is the prevention of cardiovascular and thrombotic complications, which will unquestionably have a positive impact on these patients’ prognoses.

In other contexts, data from both clinical trials and real-life studies demonstrate that rivaroxabán is effective and safe across the whole spectrum of cardiovascular disease, including atrial fibrillation, venous thromboembolic disease, and atherosclerotic cardiovascular disease. Consequently, rivaroxabán could provide additional benefits for patients by helping prevent thrombotic and cardiovascular complications during the COVID-19 pandemic.