Limbal stem cell deficiency in a contact lens-related case

Abstract

Background: Limbal stem cell deficiency is a loss or decreased function of limbal epithelial stem cells secondary to systemic or ocular disease, trauma, contact lens wear, or an iatrogenic or idiopathic cause. The condition manifests itself as a conjunctivalization, vascularization and chronic keratitis usually involving the superior cornea. This article discusses a 38-year-old female patient who presented with contact lens-induced limbal stem cell deficiency. Historically, the treatment of limbal stem cell deficiency has included allograft transplant, autograft transplant, keratoepithelioplasty, and amniotic membrane transplant. However, less invasive procedures, such as lubricant therapy and debridement, should first be considered although the length of treatment may be longer.