Assessment of morbidity and functional results in bladder replacement with Hautmann ileal neobladder after radical cystectomy: a clinical experience in 55 highly selected patients

IF 2.1 3区 医学 Q2 UROLOGY & NEPHROLOGY
Michel Soulié , Philippe Seguin , Patrick Mouly , Mathieu Thoulouzan , Francis Pontonnier , Pierre Plante
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引用次数: 24

Abstract

Objectives. To analyze the morbidity and functional results of the ileal neobladder in a series of 55 highly selected patients. The ileal neobladder is a commonly used technique for orthotopic bladder reconstruction after radical cystectomy in both sexes. Good results have been published from Ulm University, where the technique was popularized.

Methods. From February 1994 to June 2000, 55 patients (47 men and 8 women), 32 to 75 years old (mean age 58) with good performance status (American Society of Anesthesiologists score 1 and 2), underwent radical cystectomy for bladder cancer and Hautmann ileal neobladder reconstruction. Functional assessments were done at 3 months and every 6 months thereafter, with special attention to urinary continence and upper urinary tract status.

Results. The median follow-up was 28.8 months (range 8 to 96). One perioperative death occurred. Early complications occurred in 23.6% without repeated surgery and late complications occurred in 25.4%, with three repeated operations for occlusive syndromes. The daytime and nighttime continence rates at 3, 6, and 12 months were 59.6%, 80.8%, and 88.5% and 38.5%, 61.5%, and 78.8%, respectively. The overall continence rate in patients younger than 70 years old was 80.8%. Three patients required self-catheterization to empty their neobladder. Eleven patients died of metastatic evolution of their bladder cancer or intercurrent disease at 6 to 36 months.

Conclusions. In highly selected patients, the ileal neobladder provides good functional results regarding continence with an acceptable complication rate. In this series, the results were comparable to those reported in the referent institution.

评估根治性膀胱切除术后用Hautmann回肠新膀胱置换膀胱的发病率和功能结果:55例高度精选患者的临床经验
目标。目的:分析55例经精挑细选的回肠新生膀胱的发病率和功能结果。回肠新膀胱是根治性膀胱切除术后常见的原位膀胱重建技术。这项技术在乌尔姆大学得到推广,并发表了良好的结果。1994年2月至2000年6月,55例患者(男47例,女8例),年龄32 ~ 75岁(平均58岁),表现良好(美国麻醉医师学会评分1分和2分),行膀胱癌根治性膀胱切除术和Hautmann回肠新膀胱重建术。3个月时进行功能评估,此后每6个月进行一次功能评估,特别关注尿失禁和上尿路状况。中位随访时间为28.8个月(8 ~ 96个月)。围手术期死亡1例。无重复手术发生早期并发症占23.6%,晚期并发症占25.4%,有3次重复手术治疗闭塞综合征。3、6、12个月的白天和夜间尿失禁率分别为59.6%、80.8%、88.5%和38.5%、61.5%、78.8%。70岁以下患者的总体尿失禁率为80.8%。3例患者需要自我导尿管排空新膀胱。11例患者在6 ~ 36个月时死于膀胱癌转移演变或合并疾病。在高度选定的患者中,回肠新膀胱提供了良好的功能结果,关于尿失禁和可接受的并发症发生率。在这个系列中,结果与参考机构报告的结果相当。
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来源期刊
Urology
Urology 医学-泌尿学与肾脏学
CiteScore
3.30
自引率
9.50%
发文量
716
审稿时长
59 days
期刊介绍: Urology is a monthly, peer–reviewed journal primarily for urologists, residents, interns, nephrologists, and other specialists interested in urology The mission of Urology®, the "Gold Journal," is to provide practical, timely, and relevant clinical and basic science information to physicians and researchers practicing the art of urology worldwide. Urology® publishes original articles relating to adult and pediatric clinical urology as well as to clinical and basic science research. Topics in Urology® include pediatrics, surgical oncology, radiology, pathology, erectile dysfunction, infertility, incontinence, transplantation, endourology, andrology, female urology, reconstructive surgery, and medical oncology, as well as relevant basic science issues. Special features include rapid communication of important timely issues, surgeon''s workshops, interesting case reports, surgical techniques, clinical and basic science review articles, guest editorials, letters to the editor, book reviews, and historical articles in urology.
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