Improving the Assessment of Trigeminal Sensitivity: a Pilot Study

IF 1 4区医学 Q4 Neuroscience

Chemosensory Perception Pub Date : 2020-05-28 DOI:10.1007/s12078-020-09281-0

Benoît Jobin, Cécilia Tremblay, Fanny Lécuyer Giguère, Jason Steffener, Johannes Frasnelli

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引用次数: 1

Abstract

The trigeminal system is a chemosensory system, next to smell and taste, allowing intranasal sensations such as freshness, spiciness, etc. The lateralization task is used to measure trigeminal sensitivity and consists in identifying the nostril stimulated by an odorous substance in a two-alternative forced-choice procedure. However, when performed in the standard method, this task takes almost 25 to 30?min to administer and only gives access to few information.

The aim of this pilot study was to compare two alternative methods of administering the lateralization task with the standard method in a group of 53 participants (41.6?years; 32 women). Specifically, we compared (1) the standard method of 40 constant stimuli with a duration of 500?ms, (2) a short version of 20 variable stimuli ranging from 200 to 600?ms (different duration method—DD), and (3) an automatic adaptive staircase method where the test adjusts the duration of stimulation according to the participant’s responses (adaptive duration method—AD).

Based on the number of correct answers and the thresholds obtained with the automatic staircase method, the average scores for the two alternative methods correlate with the score at the standard method. In addition, both alternative methods are able to discriminate between participants with a high sensitivity and those with a lower sensitivity. Finally, the DD method is significantly shorter in terms of administration time than the other two methods.

This pilot study presents two novel methods to evaluate trigeminal sensitivity which each have a specific superiority over the established technique.

The DD method cuts testing time in half whereas the AD method provides threshold estimates for individual nostrils.

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改进三叉神经敏感性评估:一项初步研究

三叉神经系统是一种化学感觉系统，仅次于嗅觉和味觉，使鼻内感觉如新鲜、辛辣等。侧化任务用于测量三叉神经的敏感性，包括在两种选择的强迫选择程序中识别被气味物质刺激的鼻孔。然而，当以标准方法执行时，这项任务几乎需要25到30分钟。管理难度小，只允许访问少量信息。本初步研究的目的是在53名参与者(41.6岁)中比较两种管理侧化任务的替代方法和标准方法。32岁女性)。具体来说，我们比较了(1)40个持续时间为500?女士，(2)20个从200到600不等的可变刺激的简短版本?ms(不同持续时间法- dd)和(3)自动适应阶梯法，其中测试根据参与者的反应调整刺激的持续时间(适应持续时间法- ad)。根据自动阶梯法获得的正确答案数量和阈值，两种替代方法的平均得分与标准方法的得分相关。此外，两种替代方法都能够区分高灵敏度和低灵敏度的参与者。最后，就管理时间而言，DD方法比其他两种方法明显更短。这项初步研究提出了两种新的方法来评估三叉神经的敏感性，每一个都有一个特定的优势超过既定的技术。DD方法将测试时间缩短了一半，而AD方法提供了单个鼻孔的阈值估计。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemosensory Perception 农林科学-神经科学

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

>36 weeks

期刊介绍： Coverage in Chemosensory Perception includes animal work with implications for human phenomena and explores the following areas: Identification of chemicals producing sensory response; Identification of sensory response associated with chemicals; Human in vivo response to chemical stimuli; Human in vitro response to chemical stimuli; Neuroimaging of chemosensory function; Neurological processing of chemoreception; Chemoreception mechanisms; Psychophysics of chemoperception; Trigeminal function; Multisensory perception; Contextual effect on chemoperception; Behavioral response to chemical stimuli; Physiological factors affecting and contributing to chemoperception; Flavor and hedonics; Memory and chemoperception.