Tm:YAG laser vapoenucleation (ThuVEP) – One-year follow-up in elderly patients

Thorsten Bach , Thomas R.W. Herrmann , Christopher Netsch , Andreas J. Gross
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Abstract

Purpose

Thulium:YAG (Tm:YAG) laser vapoenucleation (ThuVEP) has been introduced in the treatment of benign prostatic obstruction (BPO) with promising results. However, with an aging population in the industrialized nations and improved medical therapy, the patients seeking treatment for BPO are getting older. Surgical therapy in this group of patients may not only be less effective due to the overall constitution of the patient but also due to the prolonged time of suffering from BPO. The aim of this study was to evaluate intermediate-term efficacy of ThuVEP in older patients. The outcome and complications of patients were analyzed after a postoperative follow-up period of 12 months and the results of subgroups aged both above and below 75 years were compared.

Material and methods

Laser prostatectomy was performed using a 70 W Tm:YAG 2 μm continuous wave laser (LISA laser, Katlenburg, Germany) in combination with a continuous-flow laser resectoscope and a mechanical tissue morcellator (R. Wolf, Knittlingen, Germany). The condition of patients was followed in terms of improvement of uroflow and post-void residual urine, intra- and postoperative course and the occurrence of complications.

Results

Eighty consecutive patients were included in this prospective observation. Patients were grouped according to age. Subgroup I included patients with an age ≥75 years, subgroup II included patients <75 years. The mean age was 80.2 years in subgroup I and 66.6 years in subgroup II. Preoperative data was comparable in both groups, as well as improvements in postoperative voiding function.

Conclusion

Transurethral ThuVEP is a safe and effective therapy method even in older patients. The patient's age does not influence the functional operative outcome.

Tm:YAG激光汽化核(ThuVEP) -老年患者1年随访
目的将铥:YAG (Tm:YAG)激光汽化核术(ThuVEP)应用于良性前列腺阻塞(BPO)的治疗,并取得了良好的效果。然而,随着工业化国家的人口老龄化和医学治疗的改善,寻求BPO治疗的患者正在变老。这类患者的手术治疗不仅由于患者的整体体质,而且由于患BPO的时间较长,可能效果较差。本研究的目的是评估ThuVEP对老年患者的中期疗效。术后随访12个月,分析患者预后及并发症,并比较75岁以上和75岁以下亚组结果。材料和方法采用70 W Tm:YAG 2 μm连续波激光器(LISA激光器,Katlenburg, Germany)联合连续流激光切除镜和机械组织粉碎器(R. Wolf, Knittlingen, Germany)进行激光前列腺切除术。观察患者尿流及空后残留尿改善情况、术中、术后病程及并发症发生情况。结果连续80例患者纳入前瞻性观察。患者按年龄分组。亚组I包括年龄≥75岁的患者,亚组II包括年龄≥75岁的患者。亚组患者平均年龄80.2岁,亚组患者平均年龄66.6岁。两组术前数据具有可比性,术后排尿功能也有改善。结论经尿道ThuVEP治疗老年患者安全有效。患者的年龄不影响功能性手术的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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