Enabling technologies for process intensification in pharmaceutical research and manufacturing

IF 8 2区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Current Opinion in Chemical Engineering Pub Date : 2023-09-01 DOI:10.1016/j.coche.2023.100920

Christos Xiouras, Koen Kuijpers, Dayne Fanfair, Matthieu Dorbec, Bjorn Gielen

引用次数: 2

Abstract

A perspective is given on the status and outlook of enabling technologies for process intensification in pharmaceutical research and manufacturing. We focus on three areas: photochemical, ultrasound, and microwave technologies that are, to date, underutilized in the pharmaceutical industry. Herein, we present a review of recent scientific and technological advances in each area with the objective to provide insight and highlight potential applications in the pharmaceutical industry. A perspective is also provided on barriers that must still be overcome to achieve the potential real-world application of these technologies.

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制药研究和制造过程强化的使能技术

对制药研究和生产过程强化的使能技术的现状和前景进行了展望。我们专注于三个领域:光化学、超声波和微波技术，迄今为止，在制药工业中尚未充分利用。在此，我们提出了最近的科学和技术进展的回顾，在每个领域的目的是提供见解和突出潜在的应用在制药工业。本文还对实现这些技术的潜在实际应用所必须克服的障碍进行了展望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Chemical Engineering BIOTECHNOLOGY & APPLIED MICROBIOLOGYENGINE-ENGINEERING, CHEMICAL

CiteScore

12.80

自引率

3.00%

发文量

114

期刊介绍： Current Opinion in Chemical Engineering is devoted to bringing forth short and focused review articles written by experts on current advances in different areas of chemical engineering. Only invited review articles will be published. The goals of each review article in Current Opinion in Chemical Engineering are: 1. To acquaint the reader/researcher with the most important recent papers in the given topic. 2. To provide the reader with the views/opinions of the expert in each topic. The reviews are short (about 2500 words or 5-10 printed pages with figures) and serve as an invaluable source of information for researchers, teachers, professionals and students. The reviews also aim to stimulate exchange of ideas among experts. Themed sections: Each review will focus on particular aspects of one of the following themed sections of chemical engineering: 1. Nanotechnology 2. Energy and environmental engineering 3. Biotechnology and bioprocess engineering 4. Biological engineering (covering tissue engineering, regenerative medicine, drug delivery) 5. Separation engineering (covering membrane technologies, adsorbents, desalination, distillation etc.) 6. Materials engineering (covering biomaterials, inorganic especially ceramic materials, nanostructured materials). 7. Process systems engineering 8. Reaction engineering and catalysis.