MRI-negative myelitis associated with MOG-IgG antibody: A case report and literature reviews

Q3 Neuroscience

eNeurologicalSci Pub Date : 2023-10-18 DOI:10.1016/j.ensci.2023.100481

Jiwon Yang, Yeong-Bae Lee, Hyeon-Mi Park

引用次数: 0

Abstract

According to few case reports, myelin oligodendrocyte glycoprotein-associated disease (MOGAD) could present as myelitis subtype with normal spine MRI, though it is rare. Herein, we report a case of clinically myelitis but MRI was normal, with strongly positive anti-MOG-IgG antibody in the sera. The patient showed a rapid improvement following a high dose methylprednisolone treatment.

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MRI阴性脊髓炎伴MOG-IgG抗体1例报告及文献复习

根据少数病例报告，髓鞘少突胶质细胞糖蛋白相关疾病（MOGAD）在正常的脊柱MRI中可能表现为脊髓炎亚型，尽管这种情况很少见。在此，我们报告了一例临床脊髓炎，但MRI正常，血清中抗MOG-IgG抗体呈强阳性。患者在接受大剂量甲基强的松龙治疗后病情迅速好转。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

eNeurologicalSci Neuroscience-Neurology

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

62 days

期刊介绍： eNeurologicalSci provides a medium for the prompt publication of original articles in neurology and neuroscience from around the world. eNS places special emphasis on articles that: 1) provide guidance to clinicians around the world (Best Practices, Global Neurology); 2) report cutting-edge science related to neurology (Basic and Translational Sciences); 3) educate readers about relevant and practical clinical outcomes in neurology (Outcomes Research); and 4) summarize or editorialize the current state of the literature (Reviews, Commentaries, and Editorials). eNS accepts most types of manuscripts for consideration including original research papers, short communications, reviews, book reviews, letters to the Editor, opinions and editorials. Topics considered will be from neurology-related fields that are of interest to practicing physicians around the world. Examples include neuromuscular diseases, demyelination, atrophies, dementia, neoplasms, infections, epilepsies, disturbances of consciousness, stroke and cerebral circulation, growth and development, plasticity and intermediary metabolism. The fields covered may include neuroanatomy, neurochemistry, neuroendocrinology, neuroepidemiology, neurogenetics, neuroimmunology, neuroophthalmology, neuropathology, neuropharmacology, neurophysiology, neuropsychology, neuroradiology, neurosurgery, neurooncology, neurotoxicology, restorative neurology, and tropical neurology.