{"title":"Subcutaneous sarcoidosis mimicking an infiltrative malignant soft-tissue tumor: Two case reports and a literature review","authors":"Yoshihiro Araki , Tomonori Misaki , Yasuhiro Ueda , Naoyuki Matsumoto , Sho Onishi , Satoru Kato","doi":"10.1016/j.joscr.2023.06.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Subcutaneous sarcoidosis is an extremely rare inflammatory disease, and the imaging characteristics are unknown.</p></div><div><h3>Case presentation</h3><p>A 72-year-old woman had an elastic hard nodule, which was gradually growing, on her left upper extremity that had been present for several years. The subcutaneous nodule showed an iso-intense signal on both T1-and T2-Magnetic resonance (MR) images. Extended enhancement to the triceps fascia was observed. A 68-year-old man noticed a hard nodule on his right thigh with tenderness one month previously. The subcutaneous nodule showed an iso-intense signal on both T1-and T2-MR images, and was enhanced with the surrounding soft-tissues, to the quadriceps fascia. Biopsy revealed a diagnosis of sarcoidosis.</p></div><div><h3>Conclusions</h3><p>Subcutaneous sarcoidosis should be kept in mind when imaging shows an infiltrative soft-tissue nodule.</p></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"2 3","pages":"Pages 87-90"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JOS Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772964823000199","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Background
Subcutaneous sarcoidosis is an extremely rare inflammatory disease, and the imaging characteristics are unknown.
Case presentation
A 72-year-old woman had an elastic hard nodule, which was gradually growing, on her left upper extremity that had been present for several years. The subcutaneous nodule showed an iso-intense signal on both T1-and T2-Magnetic resonance (MR) images. Extended enhancement to the triceps fascia was observed. A 68-year-old man noticed a hard nodule on his right thigh with tenderness one month previously. The subcutaneous nodule showed an iso-intense signal on both T1-and T2-MR images, and was enhanced with the surrounding soft-tissues, to the quadriceps fascia. Biopsy revealed a diagnosis of sarcoidosis.
Conclusions
Subcutaneous sarcoidosis should be kept in mind when imaging shows an infiltrative soft-tissue nodule.
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