{"title":"Management of Baló Concentric Sclerosis with rituximab: A case study with long-term follow-up","authors":"Lina Okar , Beatriz Canibano , Dirk Deleu","doi":"10.1016/j.nerep.2023.100177","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>: Baló concentric sclerosis (BCS) is a rare demyelinating disorder that overlaps with other demyelinating diseases. BCS usually present in the context of multiple sclerosis (MS) or preceding typical MS. It rarely presents as an isolated lesion, . IV methyl prednisolone (IVMP) is the mainstay in the treatment with various outcomes. Maintenance therapy is still not clearly defined.</p><p>Case presentation/case report: We present a case of isolated BCS that responded clinically and radiologically to long-term rituximab therapy.</p></div><div><h3>Conclusion</h3><p>: A definite guideline for treating patient with BCS either with MS or as isolated entity is still controversial. Our case reflects a remarkable response to rituximab in achieving clinical and radiological long-term remission.</p></div>","PeriodicalId":100950,"journal":{"name":"Neuroimmunology Reports","volume":"4 ","pages":"Article 100177"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroimmunology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667257X23000153","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Background
: Baló concentric sclerosis (BCS) is a rare demyelinating disorder that overlaps with other demyelinating diseases. BCS usually present in the context of multiple sclerosis (MS) or preceding typical MS. It rarely presents as an isolated lesion, . IV methyl prednisolone (IVMP) is the mainstay in the treatment with various outcomes. Maintenance therapy is still not clearly defined.
Case presentation/case report: We present a case of isolated BCS that responded clinically and radiologically to long-term rituximab therapy.
Conclusion
: A definite guideline for treating patient with BCS either with MS or as isolated entity is still controversial. Our case reflects a remarkable response to rituximab in achieving clinical and radiological long-term remission.
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