Acute changes in affective valence and perceived distress predict reductions in PTSD symptom severity

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
James W. Whitworth , Nicholas J. SantaBarbara , Sanaz Nosrat , Michelle M. Pebole , Bradley G. Cripe , Grace McKeon
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Abstract

There is a growing amount of experimental evidence demonstrating therapeutic chronic effects of exercise (e.g., resistance exercise, running, and walking) on PTSD symptoms. However, it is currently unclear how individuals with PTSD experience exercise within individual exercise sessions (e.g., pleasurable or distressing), and if these acute experiences influence PTSD symptoms over time. Purpose: The objective of this study was to examine the acute effects of high intensity resistance exercise on affect, perceived arousal, and distress among individuals who screened positive for PTSD, using a randomized controlled design. Additionally, this study sought to explore longitudinal relations among affect, arousal, distress, and PTSD symptom severity. Methods: This study analyzed pooled data from two methodologically similar randomized controlled trials (i.e., a pilot and replication study). Participants (n = 52) were randomly assigned to exercise or non-exercise time-matched control. Data were analyzed with a series of longitudinal mixed-effects regression models. Results: The analyses suggest that positive affect increased, and distress decreased significantly during exercise sessions, relative to control. Independent of group, increases in positive affect and decreases in distress also significantly predicted decreases in PTSD symptom severity over the course of the study. Conclusions: Taken together, these findings suggest that high intensity resistance exercise is safe for individuals who screen positive for PTSD, pleasurable, and may have a therapeutic impact on trauma survivors. No evidence for symptom exacerbation was found. Future experimental studies are needed to verify these findings and determine if the observed relationships are similar for other exercise modes, durations, and intensities.

情感效价和感知痛苦的急性变化预测PTSD症状严重程度的减轻
越来越多的实验证据表明,运动(如阻力运动、跑步和步行)对创伤后应激障碍症状的慢性治疗作用。然而,目前尚不清楚创伤后应激障碍患者在个人锻炼过程中是如何体验锻炼的(例如,愉快或痛苦),以及这些急性经历是否会随着时间的推移影响创伤后应激症状。目的:本研究的目的是使用随机对照设计,研究高强度阻力运动对PTSD筛查呈阳性的个体的情感、感知唤醒和痛苦的急性影响。此外,本研究试图探索情感、唤醒、痛苦和创伤后应激障碍症状严重程度之间的纵向关系。方法:本研究分析了两项方法相似的随机对照试验(即试点和复制研究)的汇总数据。参与者(n=52)被随机分配到运动或非运动时间匹配的对照组。采用一系列纵向混合效应回归模型对数据进行分析。结果:分析表明,与对照组相比,在运动过程中,积极情绪增加,痛苦显著减少。在研究过程中,与群体无关,积极情绪的增加和痛苦的减少也显著预测了创伤后应激障碍症状严重程度的降低。结论:总之,这些发现表明,高强度阻力运动对PTSD筛查呈阳性的人来说是安全的,是愉快的,并且可能对创伤幸存者产生治疗影响。没有发现症状恶化的证据。需要未来的实验研究来验证这些发现,并确定在其他运动模式、持续时间和强度下观察到的关系是否相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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