Design of a high-sensitivity polymer double-slot waveguide sensor for point-of-care biomedical applications

S. Prasanna Kumaar, A. Sivasubramanian
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Abstract

Silicon photonics is a rapidly developing field that offers cost-effective biosensors with improved sensitivity and the potential for interconnecting with other electronic devices for instant disease diagnosis. The Mach Zehnder interferometer architecture (MZI) is a key technology for biosensors, as it detects changes in refractive index (RI) caused by the presence of biomolecules. In this study, a silicon-polymer double-slot waveguide-based MZI was designed, with a small mode area and a large evanescent field to enhance light-analyte interaction. The waveguide was optimized by converting a normal slot waveguide into a double-slot waveguide with varying slot widths. In transmission spectrum, the wavelength shift was measured for both normal and disease samples. Additionally, the loss at a specific wavelength was analyzed to understand the impact of the biomolecule on the sensor performance. The results show that this sensor has a high sensitivity of 2.39 X10^5 nm/RIU, making it a promising candidate for biosensing applications.

Abstract Image

用于护理点生物医学应用的高灵敏度聚合物双槽波导传感器的设计
硅光子学是一个快速发展的领域,它提供了成本效益高、灵敏度高的生物传感器,并有可能与其他电子设备互连,用于即时疾病诊断。Mach-Zehnder干涉仪结构(MZI)是生物传感器的关键技术,因为它可以检测生物分子存在引起的折射率(RI)变化。在本研究中,设计了一种基于硅聚合物双缝波导的MZI,该波导具有小的模面积和大的倏逝场,以增强光与分析物的相互作用。通过将普通缝隙波导转换为具有不同缝隙宽度的双缝隙波导来优化波导。在透射光谱中,测量了正常和疾病样本的波长偏移。此外,还分析了特定波长下的损耗,以了解生物分子对传感器性能的影响。结果表明,该传感器具有2.39 X10^5nm/RIU的高灵敏度,是生物传感应用的一个有前途的候选者。
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CiteScore
17.40
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