Ureteral obstruction may activate kidney latent tuberculosis. A qualitative study

IF 1.9 Q3 INFECTIOUS DISEASES
André Avarese Figueiredo , Augusto de Azevedo Barreto , Humberto Elias Lopes , José Murillo Bastos Netto
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Abstract

Objectives

To analyze the hypothesis that ureteral obstruction may activate kidney latent tuberculous though qualitative study of Urogenital Tuberculosis patients.

Methods

A qualitative study was conducted using semistructured interviews in eight patients with Urogenital Tuberculosis. The progression of the disease from the initial symptoms was characterized through the analysis of the clinical and radiological data. The presence of ureteral obstruction prior to the onset of renal tuberculosis was observed in three patients.

Results

Patient 1: A 58-year-old female had five episodes of acute left ureteral lithiasis in two years prior to left kidney tuberculosis. Patient 2: A 55-year-old male patient had a 1.2 cm proximal left ureteral stone and in the following six months, the diagnosis of tuberculosis was made in a nonfunctioning left kidney with ureteral thickening and stenosis. Patient 3: A 47-year-old male patient had a 1.2 cm stone in the proximal right ureter and developed urinary tuberculosis with a nonfunctioning right kidney and a contracted bladder.

Conclusion

Kidney tuberculosis may appear in the same kidney that had previously suffered stone ureteral obstruction, which may have created local conditions for the activation of latent foci of renal tuberculosis.

输尿管梗阻可引起肾潜伏性结核。定性研究
目的通过对泌尿生殖道结核患者的定性研究,分析输尿管梗阻可能激活肾潜伏性结核的假说。方法采用半结构访谈法对8例泌尿生殖道结核患者进行定性研究。通过对临床和放射学数据的分析,对疾病从最初症状开始的进展进行了表征。在三名患者中观察到肾结核发病前存在输尿管梗阻。结果患者1:一名58岁女性,在左肾结核发生前两年内曾发生5次急性左输尿管结石。患者2:一名55岁男性患者,左输尿管近端结石1.2厘米,在随后的六个月内,诊断为肺结核,左肾功能不全,输尿管增厚和狭窄。患者3:一名47岁的男性患者,右输尿管近端有一块1.2厘米的结石,并发尿结核,右肾功能衰竭,膀胱收缩。结论肾结核可能出现在先前患有输尿管结石梗阻的同一肾脏中,这可能为肾结核潜伏灶的激活创造了局部条件。
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来源期刊
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases Medicine-Pulmonary and Respiratory Medicine
CiteScore
4.00
自引率
5.00%
发文量
44
审稿时长
30 weeks
期刊介绍: Journal of Clinical Tuberculosis and Mycobacterial Diseases aims to provide a forum for clinically relevant articles on all aspects of tuberculosis and other mycobacterial infections, including (but not limited to) epidemiology, clinical investigation, transmission, diagnosis, treatment, drug-resistance and public policy, and encourages the submission of clinical studies, thematic reviews and case reports. Journal of Clinical Tuberculosis and Mycobacterial Diseases is an Open Access publication.
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