Associations between suicidality and interoception in obsessive-compulsive disorder

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-10-01 DOI:10.1016/j.jocrd.2023.100844

Amanda N. Belanger , Kiara R. Timpano , Goi Khia Eng , Laura B. Bragdon , Emily R. Stern

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Abstract

Background

Individuals with obsessive-compulsive disorder (OCD) are at increased risk for suicide. One potential risk factor is interoceptive sensibility (IS), which is one's subjective experience of bodily sensations. The current study examined the relationship between IS and current suicidal ideation and lifetime history of suicide attempt, controlling for relevant covariates.

Methods

Participants (N = 145) were a clinical sample of individuals with OCD from the New York City area. A clinical rater administered a diagnostic interview and an OCD severity assessment, and participants completed questionnaires about demographics, IS, and suicidality.

Results

Current suicidal ideation was associated with reduced trusting of the body, and lifetime history of suicide attempt was related to greater general awareness of sensation. These associations remained significant after controlling for covariates.

Conclusions

These results suggest that specific facets of IS may be associated with specific domains of suicidality. Decreased body trusting may represent a feeling of disconnection from the body that facilitates desire for death. Increased noticing of bodily sensations may lead to greater mental pain, which could interact with deficits in emotion regulation to increase risk for suicide attempt. Further research on the relationships between IS and suicidality in OCD is warranted.

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强迫症患者自杀行为与内感的关系

背景强迫症患者自杀的风险增加。一个潜在的风险因素是内感受性（is），这是一个人对身体感觉的主观体验。目前的研究检验了IS与当前自杀意念和自杀未遂终生史之间的关系，并控制了相关的协变量。方法参与者（N=145）是来自纽约市地区的强迫症患者的临床样本。一名临床评分员进行了诊断性访谈和强迫症严重程度评估，参与者完成了关于人口统计、IS和自杀的问卷调查。结果当前的自杀意念与对身体的信任度降低有关，自杀未遂史与对感觉的总体意识增强有关。在控制协变量后，这些关联仍然显著。结论这些结果表明，IS的特定方面可能与自杀的特定领域有关。对身体的信任减少可能代表一种与身体脱节的感觉，这会促进对死亡的渴望。对身体感觉的注意增加可能会导致更大的精神痛苦，这可能与情绪调节缺陷相互作用，从而增加自杀未遂的风险。有必要进一步研究强迫症患者的IS与自杀之间的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.