Assessment of physical/mechanical properties and cytotoxicity of dual-cured resin cements containing Sr-bioactive glass nanoparticles and calcium phosphate.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-11-29 Epub Date: 2023-10-25 DOI:10.4012/dmj.2023-127

Sasipin Thanyasiri, Parichart Naruphontjirakul, Chawal Padunglappisit, Bharat Mirchandani, Anne M Young, Piyaphong Panpisut

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引用次数: 0

Abstract

The aim was to develop dual-cured resin cements containing Sr-bioactive glass nanoparticles (Sr-BGNPs; 5 or 10 wt%) and monocalcium phosphate monohydrate (MCPM; 3 or 6 wt%). Effects of additives on degree of monomer conversion (DC), biaxial flexural strength/modulus, shear bond strength (SBS), mass/volume change, color stability, ion release, and cytotoxicity were examined. Controls included material without reactive fillers and Panavia SA Plus (PV). Experimental cements showed higher DC than PV regardless of light activation (p<0.05). Mean SBS and color stability were comparable between experimental cements and PV. Cell viability upon the exposure to sample extracts of experimental cements was 80%-92%. High additive concentrations led to lower strength and modulus than PV (p<0.05). The additives increased mass change, reduced color stability, and promoted ion release. The experimental resin cements demonstrated acceptable mechanical/chemical properties and cytotoxicity. The additives reduced the strength but provided ion release, a desirable action to prevent recurrent caries.

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含有Sr生物活性玻璃纳米颗粒和磷酸钙的双固化树脂水泥的物理/机械性能和细胞毒性评估。

目的是开发含有Sr生物活性玻璃纳米颗粒（Sr-BGNPs；5或10wt%）和磷酸一钙一水合物（MCPM；3或6wt%）的双固化树脂水泥。考察了添加剂对单体转化率（DC）、双轴弯曲强度/模量、剪切结合强度（SBS）、质量/体积变化、颜色稳定性、离子释放和细胞毒性的影响。对照品包括不含活性填料的材料和Panavia SA Plus（PV）。实验水泥在不考虑光活化的情况下显示出高于PV的DC（p

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.