Salty Subjects: Unpacking Racial Differences in Salt-Sensitive Hypertension.

IF 3.9 2区医学 Q1 PERIPHERAL VASCULAR DISEASE

Current Hypertension Reports Pub Date : 2024-01-01 Epub Date: 2023-10-25 DOI:10.1007/s11906-023-01275-z

Soolim Jeong, Stacy D Hunter, Marc D Cook, Gregory J Grosicki, Austin T Robinson

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Abstract

Purpose of review: To review underlying mechanisms and environmental factors that may influence racial disparities in the development of salt-sensitive blood pressure.

Recent findings: Our group and others have observed racial differences in diet and hydration, which may influence salt sensitivity. Dietary salt elicits negative alterations to the gut microbiota and immune system, which may increase hypertension risk, but little is known regarding potential racial differences in these physiological responses. Antioxidant supplementation and exercise offset vascular dysfunction following dietary salt, including in Black adults. Furthermore, recent work proposes the role of racial differences in exposure to social determinants of health, and differences in health behaviors that may influence risk of salt sensitivity. Physiological and environmental factors contribute to the mechanisms that manifest in racial differences in salt-sensitive blood pressure. Using this information, additional work is needed to develop strategies that can attenuate racial disparities in salt-sensitive blood pressure.

Abstract Image

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盐敏感型高血压的种族差异。

综述目的：综述可能影响盐敏感性血压发展中种族差异的潜在机制和环境因素。最近的发现：我们小组和其他人观察到了饮食和水合作用方面的种族差异，这可能会影响盐敏感性。膳食盐会引起肠道微生物群和免疫系统的负面变化，这可能会增加高血压风险，但对这些生理反应中潜在的种族差异知之甚少。补充抗氧化剂和运动可以抵消食用盐后的血管功能障碍，包括黑人成年人。此外，最近的工作提出了种族差异在暴露于健康的社会决定因素中的作用，以及可能影响盐敏感性风险的健康行为差异。生理和环境因素促成了盐敏感血压种族差异的机制。利用这些信息，还需要开展更多的工作来制定能够减少盐敏感血压种族差异的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Hypertension Reports 医学-外周血管病

CiteScore

10.50

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of hypertension. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as antihypertensive therapies, associated metabolic disorders, and therapeutic trials. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.