Current advances in non-viral gene delivery systems: Liposomes versus extracellular vesicles

BMEMat Pub Date : 2023-06-27 DOI:10.1002/bmm2.12034
Zakia Belhadj, Yunkai Qie, Randy P. Carney, Yuanpei Li, Guangjun Nie
{"title":"Current advances in non-viral gene delivery systems: Liposomes versus extracellular vesicles","authors":"Zakia Belhadj,&nbsp;Yunkai Qie,&nbsp;Randy P. Carney,&nbsp;Yuanpei Li,&nbsp;Guangjun Nie","doi":"10.1002/bmm2.12034","DOIUrl":null,"url":null,"abstract":"<p>In article number 10.1002/bmm2.12018, Zakia Belhadj, Yunkai Qie, and their co-workers present a detailed comparison between liposomes (LSs) and extracellular vesicles (EVs) in the field of gene therapy. They summarize the advantages and limitations of these systems with particular emphasis on their in vivo fate and their advanced biomedical applications in nanomedicine. Additionally, they discuss the challenges facing the preclinical and clinical translation of these lipid-based nanocarriers, as well as their prospective use in the development of SARS-CoV-2 vaccines.\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure>\n </p>","PeriodicalId":100191,"journal":{"name":"BMEMat","volume":"1 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bmm2.12034","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMEMat","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/bmm2.12034","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

In article number 10.1002/bmm2.12018, Zakia Belhadj, Yunkai Qie, and their co-workers present a detailed comparison between liposomes (LSs) and extracellular vesicles (EVs) in the field of gene therapy. They summarize the advantages and limitations of these systems with particular emphasis on their in vivo fate and their advanced biomedical applications in nanomedicine. Additionally, they discuss the challenges facing the preclinical and clinical translation of these lipid-based nanocarriers, as well as their prospective use in the development of SARS-CoV-2 vaccines.

Abstract Image

非病毒基因递送系统的最新进展:脂质体与细胞外小泡
在文章编号10.1002/bmm2.12018中,Zakia Belhadj、Yunkai Qie及其同事对基因治疗领域中脂质体(LSs)和细胞外囊泡(EVs)进行了详细比较。他们总结了这些系统的优势和局限性,特别强调了它们的体内命运及其在纳米医学中的先进生物医学应用。此外,他们还讨论了这些基于脂质的纳米载体在临床前和临床转化方面面临的挑战,以及它们在严重急性呼吸系统综合征冠状病毒2型疫苗开发中的潜在用途。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信