Cover Feature: Multiplexed Label-Free Biomarker Detection by Targeted Disassembly of Variable-Length DNA Payload Chains (Anal. Sens. 4/2023)

Abstract

The cover feature image illustrates the detection principle behind a novel multiplexed biomarker detection platform. The presence of specific biomarkers releases distinctly-sized DNA fragments, resulting in a characteristic band pattern in electrophoresis experiments. In combination with capillary electrophoresis, this could enable automated detection of multiple biomarkers in parallel, at a fraction of the cost and complexity of conventional diagnostic systems. Cover design by Matthew Aquilina. More information can be found in the Research Article by Matthew Aquilina and Katherine E. Dunn.