Pellagra as a potential complication of anorexia nervosa: A comprehensive literature review

IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM
Manu Onteeru
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Abstract

Pellagra, a deficiency of niacin (Vitamin B3), is a potential secondary complication of anorexia nervosa (AN) resulting from restricted nutrient consumption. Symptoms observed in patients with pellagra (such as diarrhea, dermatitis, dementia, and death) can often overlap with or be affected by AN status. This article presents the largest literature review to date on symptoms observed with AN-induced pellagra, treatment regimens, and patient outcomes. An English literature search was performed using the keywords “pellagra” and “anorexia”, yielding seven female case reports. The most prevalent symptom (100%) reported was erythema of the face, neck, and arm regions. Symptoms traditionally associated with pellagra were not identified as frequently, such as diarrhea (29%). The most common treatment regime included both Vitamin B supplementation and dietary advice (83%), with all patients recorded recovering from pellagra. AN and pellagra may affect the symptomatic presentation of its counterpart disease, providing a challenge to practitioners tasked with diagnosing patients. Future studies are needed to clarify the symptomatic development of the diseases concurrently, and best practices in treatment and diagnosis.

糙皮病是神经性厌食症的潜在并发症:综合文献综述
糙皮病是一种烟酸(维生素B3)缺乏,是神经性厌食症(AN)的潜在继发并发症,由营养摄入受限引起。糙皮病患者的症状(如腹泻、皮炎、痴呆和死亡)通常与AN状态重叠或受AN状态影响。这篇文章介绍了迄今为止最大的文献综述,观察到的an诱导糙皮病的症状,治疗方案和患者的结果。使用关键词“糙皮病”和“厌食症”进行英文文献检索,得到7例女性病例报告。最常见的症状(100%)是面部、颈部和手臂区域的红斑。传统上与糙皮病相关的症状并不常见,如腹泻(29%)。最常见的治疗方案包括补充维生素B和饮食建议(83%),所有记录的患者都从糙皮病中恢复。AN和糙皮病可能影响其对应疾病的症状表现,为诊断患者的从业者提供了挑战。未来的研究需要阐明疾病的症状发展,以及治疗和诊断的最佳实践。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Human Nutrition and Metabolism
Human Nutrition and Metabolism Agricultural and Biological Sciences-Food Science
CiteScore
1.50
自引率
0.00%
发文量
30
审稿时长
188 days
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