Desarrollo genital prenatal. Clasificación, diagnóstico y manejo de las anomalías de la diferenciación sexual

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia Pub Date : 2023-04-01 DOI:10.1016/j.gine.2022.100828

M. Pineda Mateo, F. Palomo Rodríguez, A. Redondo Villatoro, I. Corrales Gutiérrez, M. Pantoja Garrido

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引用次数: 0

Abstract

To review the most current literature on the aetiopathogenesis and classification of abnormalities of sexual differentiation, as well as prenatal genital development. A literature search through PubMed, MedLine, Embase, BioMed Central, and SciELO databases was conducted.

Abnormalities of sexual differentiation comprise a wide spectrum of diseases that can develop at different stages of life. These anomalies require complex evaluation by a multidisciplinary team in which the obstetrician plays a fundamental role in prenatal diagnosis. Discrepancy between the genetic sex determined by non-invasive prenatal testing and the phenotypic sex observed by ultrasound is an increasingly frequent finding, with an incidence of 1 in 1,500-2,000 pregnancies. Early detection of this discrepancy can guide clinical suspicion and improve the management of different sexual developmental anomalies from the prenatal period.

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产前生殖发育。性别分化异常的分类、诊断和处理

回顾了目前关于性别分化异常的病因、分类以及产前生殖器发育的最新文献。通过PubMed、MedLine、Embase、BioMed Central和SciELO数据库进行文献检索。性别分化异常包括各种各样的疾病，可以在生命的不同阶段发展。这些异常需要由多学科团队进行复杂的评估，其中产科医生在产前诊断中起着重要作用。无创产前检查确定的基因性别与超声观察到的表现型性别之间的差异越来越频繁，发生率为1 / 1,500-2,000。早期发现这种差异可以指导临床怀疑，并从产前开始改善对不同性发育异常的管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinica e Investigacion en Ginecologia y Obstetricia OBSTETRICS & GYNECOLOGY-

CiteScore

0.20

自引率

0.00%

发文量

期刊介绍： Una excelente publicación para mantenerse al día en los temas de máximo interés de la ginecología de vanguardia. Resulta idónea tanto para el especialista en ginecología, como en obstetricia o en pediatría, y está presente en los más prestigiosos índices de referencia en medicina.