Fallo ovárico, una problemática para las mujeres en edad reproductiva y su relación genética

Abstract

Primary ovarian failure is a condition in which women under 40 experience oligomenorrhea or amenorrhea for 4 months or longer; this early ovarian function loss may be related to a series of etiologies, including genetic disorders, autoimmune diseases, infections or iatrogenic causes; however 74%-90% are idiopathic. Despite being a less prevalent disorder, it is of great clinical importance since it affects all women in multiple aspects of life. At present, different studies are being developed in order to find new molecular targets to establish new therapies for the treatment of this pathology.