Prevalence of Enterobius vermicularis among children in Iran: A comprehensive systematic review and meta-analysis

IF 2 Q3 INFECTIOUS DISEASES

Parasite Epidemiology and Control Pub Date : 2023-08-01 DOI:10.1016/j.parepi.2023.e00315

Elnaz Moussavi , Mohammad Houssaini , Nader Salari , Mahvan Hemmati , Ahmad Abdullahi , Ali Asghar Khaleghi , Shamarina Shohaimi , Masoud Mohammadi

{"title":"Prevalence of Enterobius vermicularis among children in Iran: A comprehensive systematic review and meta-analysis","authors":"Elnaz Moussavi , Mohammad Houssaini , Nader Salari , Mahvan Hemmati , Ahmad Abdullahi , Ali Asghar Khaleghi , Shamarina Shohaimi , Masoud Mohammadi","doi":"10.1016/j.parepi.2023.e00315","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Parasitic infections are among the most common diseases worldwide, and enterobiasis is a well-known type of parasitic infection in children. Given the existence of several reports on the prevalence of <em>Enterobius vermicularis</em> in different provinces of Iran and the heterogeneity of the reported prevalence data, this study aims to investigate the overall prevalence of <em>Enterobius vermicularis</em> among children in Iran through a systematic review and meta-analysis.</p></div><div><h3>Methods</h3><p>This systematic review and meta-analysis study involved a comprehensive search of several databases, including PubMed, ScienceDirect, SID, and Google Scholar, focusing on cross-sectional studies that examined the prevalence of <em>Enterobius vermicularis</em> infection in Iranian children. The identified studies were entered into the EndNote software for review. The quality of observational studies was evaluated using the STROBE checklist. The information extracted from the studies was entered into the Comprehensive Meta-analysis (CMA, Version 2) software. Heterogeneity among the studies was analyzed using the I<sup>2</sup> test, and publication bias was assessed using the Egger test and funnel plot.</p></div><div><h3>Results</h3><p>A total of 51 studies, with a sample size of 46,070 children, were included in the review. Using the random effects method, the overall prevalence of <em>Enterobius vermicularis</em> among children in Iran was determined to be 6.7% (95%CI: 5.2–8.6). The review of the factors affecting study heterogeneity and sample size indicated that as sample size increased, the prevalence of <em>Enterobius vermicularis</em> among children in Iran also increased (<em>p</em> = 0.578). Additionally, with an increase in the year of conducting the studies, the prevalence of <em>Enterobius vermicularis</em> among children in Iran decreased (<em>p</em> < 0.05).</p></div><div><h3>Conclusion</h3><p>The findings of this study show a relatively high prevalence of <em>Enterobius vermicularis</em> among children in Iran. We recommend health policymakers recognize the significance of this issue and take necessary measures to reduce the incidence of this infectious agent in children, implementing more effective preventive measures through mass media and educational campaigns.</p></div>","PeriodicalId":37873,"journal":{"name":"Parasite Epidemiology and Control","volume":null,"pages":null},"PeriodicalIF":2.0000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Parasite Epidemiology and Control","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405673123000326","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Parasitic infections are among the most common diseases worldwide, and enterobiasis is a well-known type of parasitic infection in children. Given the existence of several reports on the prevalence of Enterobius vermicularis in different provinces of Iran and the heterogeneity of the reported prevalence data, this study aims to investigate the overall prevalence of Enterobius vermicularis among children in Iran through a systematic review and meta-analysis.

Methods

This systematic review and meta-analysis study involved a comprehensive search of several databases, including PubMed, ScienceDirect, SID, and Google Scholar, focusing on cross-sectional studies that examined the prevalence of Enterobius vermicularis infection in Iranian children. The identified studies were entered into the EndNote software for review. The quality of observational studies was evaluated using the STROBE checklist. The information extracted from the studies was entered into the Comprehensive Meta-analysis (CMA, Version 2) software. Heterogeneity among the studies was analyzed using the I² test, and publication bias was assessed using the Egger test and funnel plot.

Results

A total of 51 studies, with a sample size of 46,070 children, were included in the review. Using the random effects method, the overall prevalence of Enterobius vermicularis among children in Iran was determined to be 6.7% (95%CI: 5.2–8.6). The review of the factors affecting study heterogeneity and sample size indicated that as sample size increased, the prevalence of Enterobius vermicularis among children in Iran also increased (p = 0.578). Additionally, with an increase in the year of conducting the studies, the prevalence of Enterobius vermicularis among children in Iran decreased (p < 0.05).

Conclusion

The findings of this study show a relatively high prevalence of Enterobius vermicularis among children in Iran. We recommend health policymakers recognize the significance of this issue and take necessary measures to reduce the incidence of this infectious agent in children, implementing more effective preventive measures through mass media and educational campaigns.

Abstract Image

查看原文本刊更多论文

伊朗儿童蛲虫患病率:一项综合系统回顾和荟萃分析

寄生虫感染是世界范围内最常见的疾病之一，肠虫病是一种众所周知的儿童寄生虫感染类型。鉴于已有多篇关于伊朗不同省份蛲虫流行的报道，以及报道的流行数据的异质性，本研究旨在通过系统回顾和荟萃分析来调查伊朗儿童蛲虫的总体流行情况。方法本系统综述和荟萃分析研究包括对PubMed、ScienceDirect、SID和谷歌Scholar等多个数据库的全面检索，重点研究伊朗儿童蛲虫感染流行情况的横断面研究。确定的研究被输入EndNote软件进行审查。观察性研究的质量采用STROBE检查表进行评估。从研究中提取的信息被输入综合meta分析(CMA, Version 2)软件。采用I2检验分析各研究间的异质性，采用Egger检验和漏斗图评估发表偏倚。结果共纳入51项研究，样本量为46070名儿童。采用随机效应法，确定伊朗儿童蛲虫总体患病率为6.7% (95%CI: 5.2-8.6)。对影响研究异质性和样本量的因素的回顾表明，随着样本量的增加，伊朗儿童蛲虫患病率也增加(p = 0.578)。此外，随着研究年份的增加，伊朗儿童中蠕虫的流行率下降了(p <0.05)。结论本研究结果显示伊朗儿童中蛭状肠虫的患病率较高。我们建议卫生政策制定者认识到这一问题的重要性，并采取必要措施，通过大众传播媒介和教育运动实施更有效的预防措施，减少儿童感染这一传染病的几率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Parasite Epidemiology and Control Medicine-Infectious Diseases

CiteScore

5.70

自引率

3.10%

发文量

审稿时长

17 weeks

期刊介绍： Parasite Epidemiology and Control is an Open Access journal. There is an increasing amount of research in the parasitology area that analyses the patterns, causes, and effects of health and disease conditions in defined populations. This epidemiology of parasite infectious diseases is predominantly studied in human populations but also spans other major hosts of parasitic infections and as such this journal will have a broad remit. We will focus on the major areas of epidemiological study including disease etiology, disease surveillance, drug resistance and geographical spread and screening, biomonitoring, and comparisons of treatment effects in clinical trials for both human and other animals. We will also look at the epidemiology and control of vector insects. The journal will also cover the use of geographic information systems (Epi-GIS) for epidemiological surveillance which is a rapidly growing area of research in infectious diseases. Molecular epidemiological approaches are also particularly encouraged.