Peritonitis primaria por neumococo en un hospital pediátrico de Argentina

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-07-01 DOI:10.1016/j.ram.2023.01.001

Mónica E. Martínez , Sandra L. Grenón , Jessica Benítez , Celia Labán , Marta E. Mollerach , Martha H. von Specht

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引用次数: 0

Abstract

Pneumococcal peritonitis represents a small subset of patients suffering from invasive pneumococcal disease (IPD). We describe 5 cases of primary peritonitis documented in the pediatric hospital over 15 years (2005-2020) of IPD surveillance. The patients, 3 girls and 2 boys with a mean age of 5 years, experienced peritoneal signs and symptoms; 3 of them suffered from nephrotic syndrome. Based on the local resistance profiles, all isolates were sensitive to beta-lactams, one strain showed resistance to cotrimoxazole and tetracycline while another strain, to cotrimoxazole only. Serotypes found in 4/5 strains (one was non-viable) were: 1, 19F, 15C and 23A. Children were treated with third-generation cephalosporins or ampicillin, gentamicin and metronidazole and all of them evolved favorably. Pneumococcal etiology should be included in the differential diagnosis of acute abdominal pain in children. Our study aims to contribute to the knowledge of this condition and to the local epidemiology of IPD.

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阿根廷一家儿科医院的原发性肺炎腹膜炎

肺炎球菌性腹膜炎是侵袭性肺炎球菌疾病（IPD）患者的一小部分。我们描述了儿科医院在IPD监测的15年（2005-2020）中记录的5例原发性腹膜炎病例。患者，3名女孩和2名男孩，平均年龄5岁，出现腹膜体征和症状；其中3例为肾病综合征。根据局部耐药性谱，所有分离株对β-内酰胺敏感，其中一株对复方新诺明和四环素表现出耐药性，而另一株仅对复方新诺明表现出耐药性。在4/5株（其中一株不活）中发现的血清类型为：1、19F、15C和23A。儿童接受了第三代头孢菌素或氨苄青霉素、庆大霉素和甲硝唑的治疗，所有这些药物都有良好的进化。肺炎球菌病因应纳入儿童急性腹痛的鉴别诊断。我们的研究旨在为了解这种情况和IPD的当地流行病学做出贡献。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.