Siyuan Wang, Kun Zhou, Xinyan Lyu, Haowen Li, Zijie Qiu*, Zheng Zhao* and Ben Zhong Tang*,
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引用次数: 0
Abstract
Observations of the micro world, especially the structures of organelles, have been attractive topics since the 17th century. As a powerful detection tool, the fluorescence technique has played a significant role in bioimaging to provide more details and enhance the signal-to-noise ratio compared to that of traditional optical microscopes. The boom of aggregate-induced emission luminogens (AIEgens) in the last two decades has revolutionized the design strategy of luminescent materials for biological applications. This Review summarizes the advantages and recent progress of AIEgens in imaging and tracking. Different imaging strategies of AIEgens including turn-on imaging, stimuli-response sensing, and long-term tracking are presented. NIR AIEgens used for in-depth bioimaging via different methods are also discussed. Finally, we propose several potential development directions for AIEgens in bioimaging.
期刊介绍：
Chemical & Biomedical Imaging is a peer-reviewed open access journal devoted to the publication of cutting-edge research papers on all aspects of chemical and biomedical imaging. This interdisciplinary field sits at the intersection of chemistry physics biology materials engineering and medicine. The journal aims to bring together researchers from across these disciplines to address cutting-edge challenges of fundamental research and applications.Topics of particular interest include but are not limited to:Imaging of processes and reactionsImaging of nanoscale microscale and mesoscale materialsImaging of biological interactions and interfacesSingle-molecule and cellular imagingWhole-organ and whole-body imagingMolecular imaging probes and contrast agentsBioluminescence chemiluminescence and electrochemiluminescence imagingNanophotonics and imagingChemical tools for new imaging modalitiesChemical and imaging techniques in diagnosis and therapyImaging-guided drug deliveryAI and machine learning assisted imaging
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