Individualized acupuncture for unilateral musculoskeletal pain: The advanced mathematical model

Lara Lopes , Joana Todi Monte , Sara Rodrigues , Celeste Baccarin Marangoni , Margarita Domingues Sousa , Ema Calçada , Larry Ibarra , Jorge Machado
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Abstract

Chronic musculoskeletal pain persists for longer than three months and is perceived to emerge from structures like bones, joints, and muscles. This condition interferes considerably in patients’ lives, leading to physical malfunction, psychological suffering, fatigue, social isolation, and job loss, resulting in a decrease in quality of life. Effective treatment remains a major challenge, highlighting the need for research to understand the complex underlying mechanisms. Recent studies have identified central neuroimmune activation and neuroinflammation as key contributors to the development of chronic pain, leading to central sensitization and reduced efficacy of opioid treatments. The number of clinical studies on the use of acupuncture for various types of pain has increased significantly in the last two decades showing a beneficial effect on pain relief and improving functional activities and psychological wellness. In our study, we decided to use a channel system and mathematical reasoning to resolve some chronic musculoskeletal pain. This method is grounded on an investigation of the historically described balancing systems, conducted by Schroeder et al. (2013) thus showing the extreme relevance of integrating psychoneuroimmunology and biopsychosocial details as necessary approaches to completely understand disease and illness. The results showed high efficiency and confirmed that the combination of more than two channels, somatotopic knowledge for the search for the right points on a balancing channel and the use of at least two types of needles helps preserve the balance of the treatment. More work should be done including studies in degenerative osteoarticular conditions.

个体化针灸治疗单侧肌肉骨骼疼痛:先进的数学模型
慢性肌肉骨骼疼痛持续时间超过三个月,可从骨骼、关节和肌肉等结构中出现。这种情况会严重干扰患者的生活,导致身体机能失常、心理痛苦、疲劳、社交孤立和失业,从而降低生活质量。有效的治疗仍然是一个重大挑战,这突出表明需要进行研究来了解复杂的潜在机制。最近的研究表明,中枢神经免疫激活和神经炎症是慢性疼痛发展的关键因素,导致中枢敏化和阿片类药物治疗的疗效降低。在过去的二十年里,关于针灸治疗各种类型疼痛的临床研究数量显著增加,显示出对缓解疼痛、改善功能活动和心理健康的有益效果。在我们的研究中,我们决定使用通道系统和数学推理来解决一些慢性肌肉骨骼疼痛。该方法基于Schroeder等人对历史上描述的平衡系统进行的调查。(2013)因此表明,将心理神经免疫学和生物心理社会细节整合为完全理解疾病的必要方法具有极大的相关性。结果显示效率很高,并证实了两个以上通道的组合、用于在平衡通道上搜索正确点的躯体主题知识以及使用至少两种类型的针有助于保持治疗的平衡。应该做更多的工作,包括对退行性骨关节疾病的研究。
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