Hipotermia terapéutica y su papel en la neuroprotección del paciente crítico pediátrico

Gerardo Guzmán de la Rosa , Mauricio Fernández Laverde , Juan Diego Ciro Quintero
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引用次数: 0

Abstract

Therapeutic hypothermia has been defined as an induced and controlled drop in core body temperature below 36 °C. The main potential benefit of therapeutic hypothermia is neuroprotection, decreasing neuronal damage and optimizing patient outcomes. It is a strategy that has been used with good results in neonates and there is evidence for some clinical conditions in adults, however, the evidence in the pediatric population has not been conclusive and even though studies have been carried out on this type of therapy, it still exists doubts about its benefits and possible complications, as well as about its effectiveness. In this article, an updated review of the subject is carried out, evaluating the pediatric evidence, with special emphasis on its usefulness in severe traumatic brain injury, post cardiac arrest syndrome and status epilepticus, entities for which therapeutic hypothermia has been used as a possible management strategy.

治疗性低温及其在儿科危重患者神经保护中的作用
治疗性体温过低被定义为核心体温在36°C以下的诱导和控制性下降。治疗性低温的主要潜在益处是神经保护、减少神经元损伤和优化患者预后。这是一种在新生儿中使用并取得良好效果的策略,有证据表明成人存在某些临床状况,然而,在儿科人群中的证据还不是决定性的,尽管已经对这种类型的治疗进行了研究,但它的益处、可能的并发症以及有效性仍存在疑问。在这篇文章中,对该主题进行了最新的综述,评估了儿科证据,特别强调了它在严重创伤性脑损伤、心脏骤停后综合征和癫痫持续状态中的有用性,治疗性低温已被用作可能的管理策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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