Ectopic gastric mucosa in the submucosa of the stomach: A case report.

Experimental and therapeutic medicine Pub Date : 2023-10-02 eCollection Date: 2023-11-01 DOI:10.3892/etm.2023.12238

Jian-Hua Xi, Nai-Ying Sun, Wen-Jun Guo, Xing-Jie Yang

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Abstract

Under normal circumstances, gastric mucosa only exists within the stomach. However, in certain situations, gastric mucosal tissue may undergo ectopia, commonly occurring in the esophagus and intestine, with rare occurrences within the stomach itself. A comprehensive literature review was performed to understand the distinct characteristics of ectopic gastric mucosa (EGM) in the stomach and investigate a rare incident of this disease, providing an in-depth analysis of the clinical, histopathologic, and differential diagnostic findings. The case was a 47-year-old man with acid reflux, heartburn, abdominal distension, and diarrhea (5-10 times daily) for >10 years. A gastroscope indicated a submucosal protuberance lesion in the gastric body that felt hard with biopsy forceps. A well-defined nodule under the mucosal muscle was revealed microscopically, composed of epithelial elements and no atypia. Immunohistochemical staining demonstrated similar EGM expression patterns compared with normal gastric mucosa. The present case report highlights the importance of accurate EGM diagnosis and understanding.

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胃黏膜下层异位的胃黏膜：一例报告。

在正常情况下，胃黏膜只存在于胃内。然而，在某些情况下，胃粘膜组织可能会发生异位，通常发生在食道和肠道，很少发生在胃内。进行了全面的文献综述，以了解胃异位胃粘膜（EGM）的独特特征，并调查这种疾病的罕见事件，对临床、组织病理学和鉴别诊断结果进行深入分析。病例是一名47岁的男性，有胃酸倒流、胃灼热、腹胀和腹泻（每天5-10次），持续时间>10年。胃镜显示胃体黏膜下突起病变，活检钳感觉很硬。显微镜下可见粘膜肌下清晰可见的结节，由上皮细胞组成，无异型性。免疫组织化学染色显示，与正常胃黏膜相比，EGM的表达模式相似。本病例报告强调了准确诊断和理解电描记图的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Experimental and therapeutic medicine

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