A New Method for Optimizing the Size of Axial FOV in TOF-PEM to Improve Performance of the Scanner.

Q3 Medicine

Journal of Biomedical Physics and Engineering Pub Date : 2023-10-01 DOI:10.31661/jbpe.v0i0.2009-1190

Delband Roshani, Saeed Setayeshi

{"title":"A New Method for Optimizing the Size of Axial FOV in TOF-PEM to Improve Performance of the Scanner.","authors":"Delband Roshani, Saeed Setayeshi","doi":"10.31661/jbpe.v0i0.2009-1190","DOIUrl":null,"url":null,"abstract":"Background: Positron Emission Mammography (PEM) is a nuclear medicine imaging tool, playing a significant role in the diagnosis of patients with breast cancer. These days, many research has been done in order to improve the performance of this system.Objective: This study aims to propose a new method for optimizing the size of axial Field of View (FOV) in PEMs and improving the performance of the systems.Material and methods: In this analytical study, a conventional Inveon PET is simulated using GATE in order to validate the simulation. For this simulation, the mean relative difference is 2.91%, showing the precision and correction of simulation and consequently it is benchmarked. In the next step, for design of the new optimized detector, several validated simulations are performed in order to find the best geometry.Results: The best result is obtained with the axial FOV of 101.7 mm. It has 1.6×1.6×15 mm3 lutetium yttrium orthosilicate (LYSO) crystals. The detector consists of 6 block rings with 30 detector blocks in each ring. In this paper, the performance of the scanner is improved and the geometry is optimized. Sensitivity and scatter fraction of the designed scanner are 4.65% and 21.2%, respectively, also noise equivalent count rate (NECR) is 105.442 kcps.Conclusion: The results showed 1 up to 3% improvement in the sensitivity of this new detector compared with different PEMs.","PeriodicalId":38035,"journal":{"name":"Journal of Biomedical Physics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/70/JBPE-13-471.PMC10589686.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomedical Physics and Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31661/jbpe.v0i0.2009-1190","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Positron Emission Mammography (PEM) is a nuclear medicine imaging tool, playing a significant role in the diagnosis of patients with breast cancer. These days, many research has been done in order to improve the performance of this system.

Objective: This study aims to propose a new method for optimizing the size of axial Field of View (FOV) in PEMs and improving the performance of the systems.

Material and methods: In this analytical study, a conventional Inveon PET is simulated using GATE in order to validate the simulation. For this simulation, the mean relative difference is 2.91%, showing the precision and correction of simulation and consequently it is benchmarked. In the next step, for design of the new optimized detector, several validated simulations are performed in order to find the best geometry.

Results: The best result is obtained with the axial FOV of 101.7 mm. It has 1.6×1.6×15 mm³ lutetium yttrium orthosilicate (LYSO) crystals. The detector consists of 6 block rings with 30 detector blocks in each ring. In this paper, the performance of the scanner is improved and the geometry is optimized. Sensitivity and scatter fraction of the designed scanner are 4.65% and 21.2%, respectively, also noise equivalent count rate (NECR) is 105.442 kcps.

Conclusion: The results showed 1 up to 3% improvement in the sensitivity of this new detector compared with different PEMs.

Abstract Image

查看原文本刊更多论文

一种优化TOF-SEM中轴向FOV尺寸以提高扫描仪性能的新方法。

背景：正电子发射乳腺成像（PEM）是一种核医学成像工具，在癌症患者的诊断中发挥着重要作用。近年来，为了提高该系统的性能，人们进行了大量的研究。目的：本研究旨在提出一种新的方法来优化PEM中轴向视场（FOV）的大小，并提高系统的性能。材料和方法：在本分析研究中，使用GATE模拟了传统的Inveon PET，以验证模拟结果。对于该模拟，平均相对差为2.91%，显示了模拟的精度和校正，因此它是基准的。在下一步中，为了设计新的优化探测器，进行了几次经过验证的模拟，以找到最佳的几何形状。结果：在轴向视场为101.7mm时，获得了最佳的结果。它具有1.6×1.6×15mm3的原硅酸镥钇（LYSO）晶体。探测器由6个块环组成，每个环中有30个探测器块。本文改进了扫描仪的性能，优化了扫描仪的几何结构。所设计的扫描仪的灵敏度和散射率分别为4.65%和21.2%，噪声等效计数率（NECR）为105.42kcps。结论：与不同的PEM相比，该新型检测器的灵敏度提高了1%至3%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Biomedical Physics and Engineering Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

10 weeks

期刊介绍： The Journal of Biomedical Physics and Engineering (JBPE) is a bimonthly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research (experimental or theoretical) broadly concerned with the relationship of physics to medicine and engineering.