A discussion about the velocity distribution commonly used as the boundary condition in surface acoustic wave numerical simulations

IF 3 4区 医学 Q3 ENGINEERING, BIOMEDICAL
Farnaz Jazini Dorcheh, Majid Ghassemi
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引用次数: 0

Abstract

Surface acoustic waves in combination with microfluidics has become an attractive research field regarding its various medical and biological applications. It is sometimes preferred to solve just the fluid domain and apply some boundary conditions to represent other components rather than performing a coupled numerical solution. To account for the piezoelectric actuation, a conventional velocity distribution built by superposing the left-going and right-going surface waves is commonly used as the boundary condition, its correctness is assessed here by comparing it to a coupled solution. It was shown that the actual leaky surface acoustic wave in coupled solution has different wavelengths in its real and imaginary parts, sometimes gets out of being sinusoidal, and has a different form compared to the superposed formula. For the phase differences other than 0 and π between the left and right electrodes, the distance between the electrodes affects the streaming and acoustic fields in the microchannel thereby leading to deviations in particle traces. Furthermore, the ratio of the horizontal to vertical components of the surface wave was extracted from the coupled solutions and compared to its previously reported values. The sensitivity analysis showed that for small particles, this ratio does not affect the streaming pattern but changes its velocity magnitude causing a time lag. For larger particles, the ratio altered the movement direction. This study suggests not replacing the piezoelectric actuation with the boundary condition to avoid inaccuracy in resulting fields that are being used in calculations of particle tracing and acoustic radiation forces.

Abstract Image

关于声表面波数值模拟中常用的边界条件——速度分布的讨论。
表面声波与微流体的结合已成为一个有吸引力的研究领域,涉及其各种医学和生物学应用。有时,只求解流体域并应用一些边界条件来表示其他分量是优选的,而不是执行耦合数值解。为了说明压电驱动,通常使用通过叠加左向和右向表面波建立的传统速度分布作为边界条件,通过将其与耦合解进行比较来评估其正确性。结果表明,耦合溶液中的实际泄漏声表面波在实部和虚部具有不同的波长,有时会偏离正弦曲线,并且与叠加公式相比具有不同的形式。对于左右电极之间除0和π之外的相位差,电极之间的距离会影响微通道中的流场和声场,从而导致粒子轨迹的偏差。此外,从耦合解中提取表面波的水平分量与垂直分量的比率,并将其与之前报告的值进行比较。灵敏度分析表明,对于小颗粒,该比率不会影响流动模式,但会改变其速度大小,从而导致时间滞后。对于较大的粒子,该比率会改变运动方向。这项研究建议不要用边界条件代替压电驱动,以避免在粒子追踪和声辐射力的计算中使用的结果场不准确。
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来源期刊
Biomedical Microdevices
Biomedical Microdevices 工程技术-工程:生物医学
CiteScore
6.90
自引率
3.60%
发文量
32
审稿时长
6 months
期刊介绍: Biomedical Microdevices: BioMEMS and Biomedical Nanotechnology is an interdisciplinary periodical devoted to all aspects of research in the medical diagnostic and therapeutic applications of Micro-Electro-Mechanical Systems (BioMEMS) and nanotechnology for medicine and biology. General subjects of interest include the design, characterization, testing, modeling and clinical validation of microfabricated systems, and their integration on-chip and in larger functional units. The specific interests of the Journal include systems for neural stimulation and recording, bioseparation technologies such as nanofilters and electrophoretic equipment, miniaturized analytic and DNA identification systems, biosensors, and micro/nanotechnologies for cell and tissue research, tissue engineering, cell transplantation, and the controlled release of drugs and biological molecules. Contributions reporting on fundamental and applied investigations of the material science, biochemistry, and physics of biomedical microdevices and nanotechnology are encouraged. A non-exhaustive list of fields of interest includes: nanoparticle synthesis, characterization, and validation of therapeutic or imaging efficacy in animal models; biocompatibility; biochemical modification of microfabricated devices, with reference to non-specific protein adsorption, and the active immobilization and patterning of proteins on micro/nanofabricated surfaces; the dynamics of fluids in micro-and-nano-fabricated channels; the electromechanical and structural response of micro/nanofabricated systems; the interactions of microdevices with cells and tissues, including biocompatibility and biodegradation studies; variations in the characteristics of the systems as a function of the micro/nanofabrication parameters.
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