“Selection of statistical tests influences the interpretation of a study outcome” a comment on “Giriraja KV, Bhatnagar SK, Tomlinson L, Sancilio F. An open-label, multicenter, phase 2 study of a food enriched with docosahexaenoic acid in adults with sickle cell disease. Prostaglandins Leukot Essent Fatty Acids. 2023 Jun; 193:102574. Doi: 10.1016/j.plefa.2023.102574. Epub 2023 Apr 7. PMID: 37121179”

IF 3
Ashwin P Patel
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引用次数: 0

Abstract

Parametric tests such as t-tests require a normal distribution of data. However, the determination of normal distribution may not be conclusive while dealing with a small sample size. Non-parametric tests such as Wilcoxon tests may be used in this situation, as these tests do not require normal distribution.

“统计测试的选择影响对研究结果的解释”,Giriraja KV,Bhatnagar SK,Tomlinson L,Sancilio F.的评论。一项针对镰状细胞病成人富含二十二碳六烯酸的食品的开放标签、多中心、2期研究。前列腺素Leukot Essent Fatty Acids。2023 Jun;193:102574。Doi:10.1016/j.plefa.2023102574。Epub 2023 Apr 7。PMID:37121179“。
诸如t检验之类的参数检验需要数据的正态分布。然而,在处理小样本量时,正态分布的确定可能不是决定性的。这种情况下可以使用非参数检验,如Wilcoxon检验,因为这些检验不需要正态分布。
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来源期刊
Prostaglandins, leukotrienes, and essential fatty acids
Prostaglandins, leukotrienes, and essential fatty acids Clinical Biochemistry, Endocrinology, Diabetes and Metabolism
CiteScore
5.30
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64 days
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