Back To Basics: Theory of Thrombus Formation and Potential Implications for Therapies?

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Techniques in Vascular and Interventional Radiology Pub Date : 2023-06-01 DOI:10.1016/j.tvir.2023.100894

M. Silena Mosquera MD , Jose A. Diaz MD, FAHA

引用次数: 0

Abstract

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common and potentially fatal condition. Despite existing treatments, recurrence rates and complications remain high. Understanding the pathophysiology of thrombus formation is crucial for developing effective therapies. This narrative review provides an overview of the critical elements of acute and chronic DVT, presents a theoretical framework for understanding thrombus formation, and discusses potential implications for therapeutic interventions. In addition, a hypothesis of thrombus formation is formulated, encompassing all elements described in this work.

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回归基础：血栓形成理论及其对治疗的潜在意义？

静脉血栓栓塞（VTE），包括深静脉血栓形成（DVT）和肺栓塞（PE），是一种常见且可能致命的疾病。尽管有现有的治疗方法，复发率和并发症仍然很高。了解血栓形成的病理生理学对于开发有效的治疗方法至关重要。这篇叙述性综述概述了急性和慢性DVT的关键因素，提出了理解血栓形成的理论框架，并讨论了治疗干预的潜在意义。此外，还提出了血栓形成的假设，包括本工作中描述的所有元素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Techniques in Vascular and Interventional Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

2.70

自引率

0.00%

发文量

期刊介绍： Interventional radiology is an area of clinical diagnosis and management that is highly technique-oriented. Therefore, the format of this quarterly journal, which combines the visual impact of an atlas with the currency of a journal, lends itself perfectly to presenting the topics. Each issue is guest edited by a leader in the field and is focused on a single clinical technique or problem. The presentation is enhanced by superb illustrations and descriptive narrative outlining the steps of a particular procedure. Interventional radiologists, neuroradiologists, vascular surgeons and neurosurgeons will find this a useful addition to the clinical literature.