B-Mode Ultrasound and Contrast-Enhanced Ultrasound for the Detection of Splenic Involvement in Hodgkin Lymphoma: A Retrospective Analysis of 112 Patients.

IF 3.1 3区医学 Q1 ACOUSTICS

Ultraschall in Der Medizin Pub Date : 2023-10-20 DOI:10.1055/a-2173-2361

Hajo Findeisen, Christian Görg, Helen Winter, Corinna Trenker, Christoph F Dietrich, Amjad Alhyari, Friederike Eilsberger, Ehsan Safai Zadeh

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Abstract

Abstract Purpose To assess splenic involvement using B-mode ultrasound (US) and contrast-enhanced ultrasound (CEUS) compared with standard imaging with contrast-enhanced computerized tomography (CT) / 18-fluorodeoxyglucose positron-emission tomography (PET-CT) in patients with Hodgkin lymphoma. Materials and Methods Imaging data from 112 patients from 12/2003 to 10/2022 with histologically confirmed Hodgkin lymphoma during staging or relapse were analyzed for splenic lymphoma involvement. In all patients, standard imaging (CT/PET-CT), along with B-mode US and CEUS examinations, was performed. Evidence of focal splenic lesions (FSLs) found by imaging procedures was suggestive of splenic involvement. Follow-up imaging was performed in each patient after treatment, and treatment response indicated definitive splenic involvement. Results 40 patients (35.7%) were identified by imaging modalities as having splenic involvement, which was confirmed by response during follow-up. Standard CT/PET-CT imaging detected splenic involvement in 36/112 patients (32.1%). FSLs were detected with B-mode US in 38 patients (33.9%) and CEUS in 36 patients (32.1%). The sensitivity of standard imaging, B-mode US, and CEUS was 90%, 95%, and 90%, respectively. Conclusion B-mode US examination is a diagnostic method used in addition to standard imaging for the detection of splenic involvement in Hodgkin lymphoma. CEUS does not provide additional benefit compared to B-mode US and the standard reference procedure.

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B型超声和对比增强超声检测霍奇金淋巴瘤脾脏受累：112例患者的回顾性分析。

目的：评估霍奇金淋巴瘤患者应用B型超声（US）和增强超声（CEUS）与计算机断层扫描（CT）/18氟脱氧葡萄糖正电子发射断层扫描（PET-CT）标准成像的脾脏受累情况。材料和方法：分析2003年12月至2022年10月112例经组织学证实的霍奇金淋巴瘤在分期或复发期间的影像学数据，以了解脾脏淋巴瘤的受累情况。在所有患者中，都进行了标准成像（CT/PET-CT），以及B型超声和CEUS检查。影像学检查发现的局灶性脾脏病变（FSL）提示脾脏受累。每个患者在治疗后都进行了随访成像，治疗反应表明明确的脾脏受累。结果：40名患者（35.7%）通过影像学检查被确定为脾脏受累，随访中的反应证实了这一点。标准CT/PET-CT显像检出脾脏受累36/112例（32.1%），B型超声检出FSL 38例（33.9%），CEUS检出FSL 36例（32.2%），标准显像、B型超声和CEUS的敏感性分别为90%、95%和90%。结论：除标准影像学检查外，B型超声检查是检测霍奇金淋巴瘤脾脏受累的一种诊断方法。与B模式US和标准参考程序相比，CEUS没有提供额外的益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ultraschall in Der Medizin 医学-核医学

CiteScore

5.30

自引率

8.80%

发文量

228

审稿时长

6-12 weeks

期刊介绍： Ultraschall in der Medizin / European Journal of Ultrasound publishes scientific papers and contributions from a variety of disciplines on the diagnostic and therapeutic applications of ultrasound with an emphasis on clinical application. Technical papers with a physiological theme as well as the interaction between ultrasound and biological systems might also occasionally be considered for peer review and publication, provided that the translational relevance is high and the link with clinical applications is tight. The editors and the publishers reserve the right to publish selected articles online only. Authors are welcome to submit supplementary video material. Letters and comments are also accepted, promoting a vivid exchange of opinions and scientific discussions.