Enhancer sequence identified as target in SLE

IF 29.4 1区医学 Q1 RHEUMATOLOGY

Nature Reviews Rheumatology Pub Date : 2023-10-18 DOI:10.1038/s41584-023-01047-8

Robert Phillips

引用次数: 0

Abstract

Chromatin accessibility of an enhancer that regulates the expression of a disease-associated microRNA is affected in monocytes from patients with systemic lupus erythematosus, highlighting this enhancer as a potential therapeutic target.

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在SLE中被鉴定为靶点的增强子序列。

在系统性红斑狼疮患者的单核细胞中，调控疾病相关 microRNA 表达的增强子的染色质可及性受到了影响，这表明该增强子是一个潜在的治疗靶点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Rheumatology 医学-风湿病学

CiteScore

29.90

自引率

0.90%

发文量

137

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Rheumatology is part of the Nature Reviews portfolio of journals. The journal scope covers the entire spectrum of rheumatology research. We ensure that our articles are accessible to the widest possible audience.