Chinese herbal medicine combined with cognitive-behavioural therapy for avoidant paruresis: a controlled trial.

IF 5.3 3区医学 Q1 PSYCHIATRY

General Psychiatry Pub Date : 2023-10-12 eCollection Date: 2023-01-01 DOI:10.1136/gpsych-2023-101014

Shijie Liang, Ying Zhou, Chao Yu, Xiang Gao, Fangbin Ji, Qianyuan Fang, Zhihang Zhang, Libin Yang, Youkang Zhao, Yuhui Zhao, Renwu Yin, Kaimin Chen, Zheng Lu

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Abstract

Background: Avoidant paruresis is a common clinical condition in urology and psychosomatic medicine. However, it has limited treatment options that are safe and effective with few side effects.

Aims: Our study aimed to investigate the effectiveness and safety of the Chinese herbal Yangxin Tongquan decoction combined with cognitive-behavioural therapy (CBT) for avoidant paruresis.

Methods: Sixty-eight patients with avoidant paruresis were divided into a treatment group (33 patients) and a control group (35 patients). The control group was assigned 10 weeks of CBT and systematic desensitisation. In addition to CBT and systematic desensitisation, the treatment group was given the Chinese herbal Yangxin Tongquan decoction during the 10-week study. The Shy Bladder Syndrome Scale (SBS) and the Self-rating Anxiety Scale (SAS) were administered before and after treatment to measure any change.

Results: The overall efficacy in the treatment group (n=30) was 80.0% vs 62.5% in the control group (n=33). Comparing pretreatment and post-treatment measures, both groups showed improvement in SBS scores and SAS scores (treatment group: t_(SBS) =8.397, p_(SBS) <0.001, t_(SAS) =8.216, p_(SAS)<0.001; control group: t_(SBS) =6.802, p_(SBS) <0.001, t_(SAS)=5.171, p_(SAS) <0.001). Moreover, both groups' SBS and SAS scores changed significantly over time (SBS scores: F_time =118.299, p<0.001; SAS scores: F_time =92.114, p<0.001). However, the treatment group performed better than the control group (SBS scores: F_time*group =5.709, p=0.020; SAS scores: F_time*group =7.235, p=0.009).

Conclusions: The Chinese herbal Yangxin Tongquan decoction combined with cognitive-behavioural psychotherapy positively affects the treatment of avoidant paruresis without significant adverse effects.

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中草药联合认知行为疗法治疗回避型遗尿：一项对照试验。

背景：遗尿症是泌尿外科和心身医学中常见的临床疾病。然而，它的治疗选择有限，安全有效，副作用很少。目的：本研究旨在探讨养心通泉汤联合认知行为疗法（CBT）治疗遗尿的有效性和安全性。方法：将68例回避型遗尿患者分为治疗组（33例）和对照组（35例）。对照组被分配10周的CBT和系统脱敏。在为期10周的研究中，除了CBT和系统脱敏外，治疗组还服用了中药养心通泉汤。在治疗前后使用害羞膀胱综合征量表（SBS）和焦虑自评量表（SAS）来测量任何变化。结果：治疗组（n=30）的总有效率为80.0%，对照组（n=33）为62.5%。比较治疗前和治疗后的测量，两组的SBS评分和SAS评分均有改善（治疗组：t（SBS）=8.397，p（SBS）0.001，t（SAS）=8.216，p（SAS）=6.802，p（SBS）0.001，t（SAS）=5.171，p（SAS）0.001）。此外，两组SBS和SAS评分随时间变化显著（SBS评分：Ftime=118.299，p0.001；SAS评分：Ftime=92.114，p0.001）。然而，治疗组疗效优于对照组（SBS评分：Ftime*组=5.709，p=0.020；SAS评分：Ftime*组=7.235，p=0.009）。

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来源期刊

General Psychiatry 医学-精神病学

CiteScore

21.90

自引率

2.50%

发文量

848

期刊介绍： General Psychiatry (GPSYCH), an open-access journal established in 1959, has been a pioneer in disseminating leading psychiatry research. Addressing a global audience of psychiatrists and mental health professionals, the journal covers diverse topics and publishes original research, systematic reviews, meta-analyses, forums on topical issues, case reports, research methods in psychiatry, and a distinctive section on 'Biostatistics in Psychiatry'. The scope includes original articles on basic research, clinical research, community-based studies, and ecological studies, encompassing a broad spectrum of psychiatric interests.