Preparation, Characterization, Antioxidant and Antibacterial Studies of New Metal (II) Complexes with Schiff Base for 3-amino-1-phenyl-2- pyrazoline-5-one

Q4 Pharmacology, Toxicology and Pharmaceutics
N. M. Abdalsahib, L. K. A. Karem
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引用次数: 1

Abstract

A new ligand complexes have been synthesis from reaction of metal ions of Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Hg(II), Pd(II) and Pt(II) with schiff base LH. 5-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-2-phenyl-2,4-dihydro-pyrazol-3-one, this ligand was characterized by Fourier transform infrared (FTIR), UV-vis, 1H, 13CNMR, and mass spectra. All complexes were characterized by techniques micro analysis C.H.N, UV-vis and FTIR spectral studies, atomic absorption, chloride content, molar conductivity measurements and magnetic susceptibility. The ligand acts as bidentate, coordination through nitrogen atom from azomethin group and deprotonated phenolic oxygen atom. The spectroscopic and analytical measurements showed that the geometric shape of the prepared complexes is octahedral, while the square planar of the palladium and platinum complexes. The ligand and its complexes were having been screened for their antimicrobial activities and antioxidant
新型3-氨基-1-苯基-2-吡唑啉-5-酮Schiff碱金属配合物的制备、表征、抗氧化及抗菌性能研究
以金属离子Mn(II)、Co(II),Ni(II)和Cu(II)以及Zn(II)与席夫碱LH反应,合成了一种新的配体配合物。5-[(2-羟基-萘-1-亚甲基)-氨基]-2-苯基-2,4-二氢-吡唑-3-酮,该配体通过傅立叶变换红外光谱、紫外-可见光谱、1H、13CNMR和质谱进行了表征。所有配合物均通过微量分析、C.H.N、UV-vis和FTIR光谱研究、原子吸收、氯化物含量、摩尔电导率测量和磁化率等技术进行了表征。配体作为双齿,通过来自甲亚胺基团的氮原子和去质子化的酚氧原子进行配位。光谱和分析测量表明,所制备的配合物的几何形状为八面体,而钯和铂的配合物为正方形平面。配体及其配合物已被筛选出具有抗菌活性和抗氧化性
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来源期刊
International Journal of Drug Delivery Technology
International Journal of Drug Delivery Technology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
0.70
自引率
0.00%
发文量
0
期刊介绍: International Journal of Drug Delivery Technology (IJDDT) provides the forum for reporting innovations, production methods, technologies, initiatives and the application of scientific knowledge to the aspects of pharmaceutics, including controlled drug release systems, drug targeting etc. in the form of expert forums, reviews, full research papers, and short communications.
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