Biventricular systolic and diastolic function in adolescents with sickle cell anemia and sickle cell traits – Systematic review

IF 0.6 Q4 PEDIATRICS

PROGRESS IN PEDIATRIC CARDIOLOGY Pub Date : 2023-08-25 DOI:10.1016/j.ppedcard.2023.101677

Fernanda Maria Correia Ferreira Lemos, Mário Luiz Ribeiro, Wolney de Andrade Martins

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引用次数: 0

Abstract

Background

Sickle cell anemia is the most prevalent hereditary hematological disease with high morbidity and mortality rates worldwide. Cardiac involvement and cardiomyopathy are frequent manifestations of sickle cell anemia. Echocardiographic analysis using tissue Doppler and speckle tracking is an important tool for assessing cardiac functions.

Aim of Review

This study aimed to determine cardiac function alterations in patients with sickle cell anemia and sickle cell traits to assess the usefulness of new echocardiographic techniques for the early detection of myocardial dysfunction in this disease. A systematic review was carried out using PubMed, Scientific Electronic Library Online, and Latin American and Caribbean Health Sciences Literature databases based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology and Population, Intervention, Control, and Outcomes criteria. Original cohort, case-control, cross-sectional, and case series articles published between December 1999 and March 2023 were analyzed.

Key Scientific Concepts of Review

Echocardiographic studies have focused on identifying the impact of ventricular systolic and diastolic performance on this disease. The studies analyzed in the current systematic review suggest intrinsic myocardial abnormalities in patients with sickle cell anemia, which may indicate early signs of cardiac involvement in young individuals.

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镰状细胞性贫血和镰状细胞特征青少年的双心室收缩和舒张功能——系统综述

镰状细胞性贫血是世界范围内发病率和死亡率最高的遗传性血液病。心脏受累和心肌病是镰状细胞性贫血的常见表现。超声心动图分析使用组织多普勒和斑点跟踪是评估心功能的重要工具。本研究旨在确定镰状细胞性贫血患者的心功能改变和镰状细胞特征，以评估新的超声心动图技术在这种疾病中早期检测心肌功能障碍的有用性。使用PubMed、科学电子图书馆在线和拉丁美洲和加勒比健康科学文献数据库，根据系统评价和荟萃分析方法的首选报告项目以及人口、干预、控制和结果标准进行系统评价。对1999年12月至2023年3月间发表的原始队列、病例对照、横断面和病例系列文章进行分析。超声心动图研究的重点是确定心室收缩和舒张表现对该疾病的影响。当前系统综述中分析的研究表明镰状细胞性贫血患者的内在心肌异常，这可能表明年轻人心脏受累的早期迹象。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PROGRESS IN PEDIATRIC CARDIOLOGY PEDIATRICS-

CiteScore

0.90

自引率

11.10%

发文量

审稿时长

75 days

期刊介绍： Progress in Pediatric Cardiology is an international journal of review presenting information and experienced opinion of importance in the understanding and management of cardiovascular diseases in children. Each issue is prepared by one or more Guest Editors and reviews a single subject, allowing for comprehensive presentations of complex, multifaceted or rapidly changing topics of clinical and investigative interest.