Investigations On Device Structure and Sensing Mechanism Using Gold Nanoparticles Decorated Photonic Crystal Fiber-based Biosensors

IF 3.3 4区 物理与天体物理 Q2 CHEMISTRY, PHYSICAL
Makram A. Fakhri, Evan T. Salim, Raed Khalid Ibrahim, Hiyam S. Ali, Ahmad S. Azzahrani, Raid A. Ismail, Subash C. B. Gopinath, Ahmed C. Kadhim, Zaid T. Salim
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Abstract

A modified photonic crystal fiber (PCF) was utilized as a biosensor, incorporating gold nanoparticles as an active plasmonic material. The finite element method (FEM) was employed to compute numerical interpretations of sensing performance using various liquids: liver blood, colon blood, human plasma, water, and pentanol. In the proposed biosensor configuration, the test sample (analyte) was placed within the core, surrounded by cladding air holes, and external to the hollow core fiber structure. Sensitivity calculations were conducted both before and after the addition of the gold overlayer. The maximum amplitude sensitivity was determined to be 769.57 RIU-1 for human plasma, accompanied by the optimal electric field of 400V/m. Similarly, in the same liquid, when the deposited photonic crystal fiber (PCF) was coated with a gold layer, the maximum amplitude sensitivity reached 975.53 RIU-1 at an optimal electric field of 477 V/m. Considering the proposed sensor as a refractive index sensor, it exclusively utilized an analyte sample within the core and air holes of the PCF. Here, the maximum amplitude sensitivity attained was 869.84 RIU-1, aligning with the best electric field value of 434 V/m."

纳米金修饰光子晶体光纤生物传感器的器件结构及传感机理研究
研究人员利用改进型光子晶体光纤(PCF)作为生物传感器,并将金纳米粒子作为活性等离子材料。利用有限元法(FEM)对各种液体(肝脏血液、结肠血液、人体血浆、水和戊醇)的传感性能进行了数值计算。在拟议的生物传感器配置中,测试样品(分析物)被放置在纤芯内,周围是包层气孔,外部是中空纤芯光纤结构。在添加金覆盖层之前和之后都进行了灵敏度计算。在最佳电场为 400V/m 的情况下,人体血浆的最大振幅灵敏度被确定为 769.57 RIU-1。同样,在相同的液体中,当沉积的光子晶体光纤(PCF)镀上金层时,在最佳电场为 477 V/m 时,最大振幅灵敏度达到 975.53 RIU-1。考虑到所提出的传感器是一种折射率传感器,它完全利用了 PCF 内芯和气孔中的分析样品。在这种情况下,达到的最大振幅灵敏度为 869.84 RIU-1,与最佳电场值 434 V/m 一致"。
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来源期刊
Plasmonics
Plasmonics 工程技术-材料科学:综合
CiteScore
5.90
自引率
6.70%
发文量
164
审稿时长
2.1 months
期刊介绍: Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
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