Role of Nutrients on Platelets Participation in Leukocyte Recruitment and Inflammation Resolution in Inflammatory Diseases, Including Covid-19

IF 0.4 4区医学 Q4 NUTRITION & DIETETICS

Current Topics in Nutraceutical Research Pub Date : 2022-08-08 DOI:10.37290/ctnr2641-452x.20:662-665

M-Y Sung, Kuo-Hung Liao, Jiunn-Sheng Wu, I-Shing Tzeng, Lou Sun, C. Kuo

引用次数: 0

Abstract

Interactions of platelets with circulating cells and vessel walls are implicated in various inflammatory processes. In certain circumstances, the hemostatic and inflammatory functions of platelets may overlap. Platelet–lymphocyte/leukocyte interactions can effectively regulate chronic inflammatory conditions. Platelet extracellular vesicles play a prominent role in thrombosis. In this review, we provide an overview of the molecules associated with platelet–cell interaction and the role of platelet extracellular vesicles in cardiovascular disorders and coronavirus disease 2019, which has posed a significant threat to global health due to infection with severe acute respiratory syndrome coronavirus 2. In addition to recruiting leukocytes to resolve inflammation associated with inflammatory diseases, such as coronavirus disease 2019, nutrients may also play a significant role in human metabolism.

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营养素对包括新冠肺炎在内的炎症性疾病中血小板参与白细胞补充和炎症解决的作用

血小板与循环细胞和血管壁的相互作用涉及各种炎症过程。在某些情况下，血小板的止血和炎症功能可能重叠。血小板-淋巴细胞/白细胞的相互作用可以有效调节慢性炎症。血小板细胞外小泡在血栓形成中起着重要作用。在这篇综述中，我们概述了与血小板-细胞相互作用相关的分子，以及血小板细胞外小泡在2019年心血管疾病和冠状病毒疾病中的作用，由于感染严重急性呼吸综合征冠状病毒2，该疾病对全球健康构成了重大威胁。除了募集白细胞来解决与炎症性疾病（如2019冠状病毒病）相关的炎症外，营养素还可能在人类代谢中发挥重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Topics in Nutraceutical Research 医学-药学

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Current Topics in Nutraceutical Research is an international, interdisciplinary broad-based peer reviewed scientific journal for critical evaluation of research on chemistry, biology and therapeutic applications of nutraceuticals and functional foods. The major goal of this journal is to provide peer reviewed unbiased scientific data to the decision makers in the nutraceutical and food industry to help make informed choices about development of new products. To this end, the journal will publish two types of review articles. First, a review of preclinical research data coming largely from animal, cell culture and other experimental models. Such data will provide basis for future product development and/or human research initiatives. Second, a critical evaluation of current human experimental data to help market and deliver the product for medically proven use. This journal will also serve as a forum for nutritionists, internists, neurologists, psychiatrists, and all those interested in preventive medicine. The common denominator of all of the topic to be covered by the journal must include nutraceuticals and/functional food. The following is an example of some specific areas that may be of interest to the journal. i) Role of vitamins, minerals, antioxidants and phytonutrients on cardiovascular health, cancer, diabetes, ocular health, mental health, men’s health, women’s health, infant nutrition, ii) Role of herbals on human health, iii) Dietary supplements and sleep, iv) Components of diet that may have beneficial effect on human health, v) regulation of apoptosis and cell viability, vi) Isolation and characterization of bioactive components from functional foods, vii) Nutritional genomics, and viii) Nutritional proteomics.