Road to HIV cure; from Berlin to London and beyond

T. Broek
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Abstract

Around 37 million people are living with HIV worldwide, with a million deaths due to HIV in 2017. While only ~60% of the infected population are receiving antiretroviral therapy (ART), by taking a combination of drugs suppressing different stage of the HIV lifecycle to lower the viral burden. While the treatment is very effective it does not eliminate HIV from the patient’s body and non-AIDS comorbidities (cardiovascular diseases and cancers) and unrelenting rate of new infections (around 2 million infections per year) have become a major concern and, thus new approaches are needed that no longer continuously suppress HIV but actually cure people.
治愈艾滋病毒之路;从柏林到伦敦及其他地区
全球约有3700万人感染艾滋病毒,2017年有100万人死于艾滋病毒。虽然只有约60%的感染人群正在接受抗逆转录病毒疗法(ART),通过服用抑制HIV生命周期不同阶段的药物组合来降低病毒负担。虽然这种治疗非常有效,但它并不能从患者体内消除艾滋病毒,非艾滋病合并症(心血管疾病和癌症)和持续不断的新感染率(每年约200万例感染)已成为一个主要问题,因此需要新的方法,不再持续抑制艾滋病毒,而是真正治愈人们。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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